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MSN 570 Advanced Pathophysiology Final 2024
1. Which of the following statements describes an active cellular membrane exchange process?
- A. Sodium moving out of cells and potassium moving into cells
- B. The movement of water from an area of low solute concentration to an area of high solute concentration
- C. The movement of insulin using a protein to travel across the cell membrane
- D. Oxygen moving across the pulmonary capillaries to an area of high carbon dioxide
Correct answer: A
Rationale: The correct answer is A. In active transport, energy is expended to move substances against their concentration gradient. Sodium moving out of cells and potassium moving into cells is an example of active transport because it requires energy to pump these ions across the cell membrane against their concentration gradients. Choices B, C, and D describe passive processes where substances move along their concentration gradients without the input of energy.
2. A 30-year-old man has a history of heart transplant and is receiving long-term steroids to prevent rejection. The patient is due for routine vaccines. Attenuated vaccines are contraindicated in this patient because the antigen is:
- A. live and can cause infection.
- B. mutated and infectious.
- C. inactive but still infectious.
- D. pathogenic.
Correct answer: A
Rationale: The correct answer is A: live and can cause infection. In patients like the one described with a history of heart transplant and receiving long-term steroids, who are immunocompromised, live attenuated vaccines are contraindicated. Live vaccines contain weakened (attenuated) forms of the virus or bacteria, which can replicate and cause mild infections in healthy individuals but can lead to serious infections in immunocompromised individuals. Choices B, C, and D are incorrect because attenuated vaccines are not mutated, not inactive, and not pathogenic in healthy individuals, respectively.
3. A patient is prescribed medroxyprogesterone acetate (Provera) for the treatment of endometriosis. What key instruction should the nurse provide regarding the administration of this medication?
- A. Take the medication at the same time each day to maintain consistent hormone levels.
- B. Discontinue the medication if side effects occur.
- C. Take the medication with food to prevent gastrointestinal upset.
- D. Apply the medication once a week.
Correct answer: A
Rationale: The correct instruction for medroxyprogesterone acetate (Provera) is to take the medication at the same time each day to maintain consistent hormone levels and ensure its effectiveness. Choice B is incorrect because discontinuing the medication abruptly without consulting healthcare providers can be harmful. Choice C is incorrect as taking the medication with food is not necessary for this specific drug. Choice D is incorrect as medroxyprogesterone is typically taken orally, not applied topically.
4. While planning care for an elderly patient, the nurse remembers that increased age is associated with:
- A. Increased T cell function
- B. Increased immune function
- C. Increased production of antibodies
- D. Increased levels of circulating autoantibodies
Correct answer: D
Rationale: As individuals age, their immune function tends to decrease, making them more susceptible to infections and diseases. Additionally, increased age is associated with higher levels of circulating autoantibodies, which can lead to autoimmune conditions. Choice A is incorrect as aging is not typically associated with increased T cell function. Choice C is also incorrect as aging does not necessarily result in increased production of antibodies. Therefore, the correct answers are B (Decreased immune function) and D (Increased levels of circulating autoantibodies).
5. A patient is starting on finasteride (Proscar) for the treatment of benign prostatic hyperplasia (BPH). What should the nurse include in the patient teaching?
- A. The medication will cure BPH after treatment is complete.
- B. The effects of the medication may take several weeks or months to become noticeable.
- C. The medication may cause increased hair growth.
- D. The medication may decrease libido.
Correct answer: B
Rationale: The correct answer is B. The effects of finasteride in treating BPH may take several weeks or months to become noticeable. It is important for the nurse to educate the patient about this expected time frame to manage expectations. Choice A is incorrect because finasteride does not cure BPH but helps in managing symptoms. Choice C is incorrect as one of the side effects of finasteride is decreased hair growth. Choice D is incorrect as finasteride may cause a decrease in libido as a side effect.
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