ATI RN
ATI Pharmacology Test Bank
1. A client has a new prescription for Enfuvirtide to treat HIV infection. The nurse should monitor the client for which of the following adverse reactions?
- A. Bone marrow suppression
- B. Pancreatitis
- C. Pancreatitis
- D. Bone marrow suppression
Correct answer: D
Rationale: While bone marrow suppression is not typically associated with Enfuvirtide, a more relevant concern is the risk of severe allergic reactions such as anaphylaxis. Enfuvirtide, an HIV fusion inhibitor, can cause local injection site reactions and systemic allergic responses. Monitoring for signs of allergic reactions, such as rash, fever, and difficulty breathing, is crucial to ensure the client's safety.
2. A client has a new prescription for Somatropin to stimulate growth. The client should monitor for which of the following adverse effects?
- A. Hyperglycemia.
- B. Bradycardia.
- C. Urinary frequency.
- D. Edema.
Correct answer: A
Rationale: Somatropin is known to cause hyperglycemia as a common adverse effect. Therefore, the client should be instructed to monitor for elevated blood glucose levels closely while taking this medication to ensure early detection and management of hyperglycemia.
3. A client has a new prescription for Valproic Acid. The client should be informed that which of the following laboratory tests need to be completed periodically? (Select all that apply.)
- A. Thrombocyte count.
- B. Hematocrit.
- C. Amylase.
- D. Liver function tests.
Correct answer: A
Rationale: Valproic acid can lead to thrombocytopenia, making it essential to monitor the client's thrombocyte count periodically. Additionally, valproic acid can cause pancreatitis, necessitating the monitoring of amylase levels. Furthermore, valproic acid carries a risk of hepatotoxicity, requiring regular monitoring of liver function tests.
4. A client has a new prescription for Captopril to treat hypertension. Which of the following instructions should the nurse include?
- A. Take the medication with food.
- B. Avoid salt substitutes.
- C. Increase your intake of potassium-rich foods.
- D. Expect a dry cough to develop.
Correct answer: B
Rationale: The correct instruction for the nurse to include is to advise the client to avoid salt substitutes. Salt substitutes often contain potassium, and captopril can cause hyperkalemia. By avoiding salt substitutes, the client can prevent elevated potassium levels and associated complications.
5. A client with Hodgkin's disease is receiving Cyclophosphamide IV. Which medication should be administered concurrently to prevent an adverse effect of Cyclophosphamide?
- A. Uroprotectant agent, such as mesna
- B. Opioid, such as morphine
- C. Loop diuretic, such as furosemide
- D. H1 receptor antagonist, such as diphenhydramine
Correct answer: A
Rationale: Mesna, an uroprotectant agent, is administered with nitrogen mustard chemotherapy drugs like Cyclophosphamide to prevent hemorrhagic cystitis, a common adverse effect. Mesna works by binding to and inactivating the toxic metabolites of Cyclophosphamide in the bladder, thereby reducing the risk of bladder toxicity.
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