ATI RN
Pathophysiology Exam 1 Quizlet
1. A 45-year-old woman has been prescribed conjugated estrogens (Premarin) for the treatment of menopausal symptoms. What should the nurse include in the patient teaching?
- A. Increase fluid intake to prevent dehydration.
- B. Avoid smoking while taking this medication.
- C. Increase the intake of high-calcium foods.
- D. Take the medication at bedtime to prevent insomnia.
Correct answer: B
Rationale: The correct answer is to 'Avoid smoking while taking this medication' because patients taking conjugated estrogens should avoid smoking due to the increased risk of cardiovascular events. Increasing fluid intake to prevent dehydration is a good practice but not specifically related to conjugated estrogens. Increasing the intake of high-calcium foods may be beneficial for bone health but is not directly related to the medication. Taking the medication at bedtime to prevent insomnia is not a specific teaching point for conjugated estrogens.
2. A patient has been diagnosed with cytomegalovirus (CMV). Which of the following drugs would be ineffective in the treatment of this disease?
- A. Ribavirin (Rebetol)
- B. Ganciclovir (Cytovene) IV
- C. Foscarnet (Foscavir) IV
- D. Valganciclovir hydrochloride (Valcyte)
Correct answer: A
Rationale: The correct answer is A, Ribavirin (Rebetol). Ribavirin is not effective against CMV. Choice B, Ganciclovir (Cytovene) IV, is a common treatment for CMV as it inhibits viral DNA synthesis. Choice C, Foscarnet (Foscavir) IV, is also used for CMV infections by blocking viral DNA polymerase. Choice D, Valganciclovir hydrochloride (Valcyte), is a prodrug of Ganciclovir and is effective against CMV. Therefore, Ribavirin is the drug that would be ineffective in treating CMV.
3. Inflammatory exudates are a combination of several types. Which of the following exudates is composed of a large accumulation of leukocytes?
- A. Serous
- B. Purulent
- C. Fibrinous
- D. Hemorrhagic
Correct answer: B
Rationale: The correct answer is B: Purulent. Purulent exudates, or pus, consist primarily of leukocytes and dead cells, indicating a bacterial infection. Serous exudates contain a thin, watery fluid with few leukocytes. Fibrinous exudates are rich in fibrin and are commonly seen in severe inflammation. Hemorrhagic exudates contain red blood cells due to blood vessel damage.
4. A nurse is educating a client with peripheral artery disease (PAD). Which statement made by the client indicates a need for further teaching?
- A. I should avoid walking for long periods to prevent leg pain.
- B. I should inspect my feet daily for any sores or wounds.
- C. I should wear compression stockings to improve circulation.
- D. I should avoid smoking to prevent further damage to my arteries.
Correct answer: A
Rationale: The correct answer is A. Walking is crucial in improving circulation in peripheral artery disease; therefore, the client should not avoid walking for long periods. Choices B, C, and D are correct statements for a client with PAD. Inspecting feet daily helps in early detection of sores or wounds, wearing compression stockings improves circulation, and avoiding smoking helps prevent further damage to arteries in PAD.
5. What is the primary cause of primary hypercholesteremia?
- A. High-density lipoprotein (HDL) defects
- B. Monogenic mutations, sedentary lifestyle, and high cholesterol diet
- C. Polygenic mutations and environmental factors
- D. Low-density lipoprotein (LDL) receptor mutation with defects in breakdown
Correct answer: D
Rationale: The correct answer is 'Low-density lipoprotein (LDL) receptor mutation with defects in breakdown.' Primary hypercholesteremia is mainly caused by mutations in the LDL receptor, leading to impaired clearance of LDL cholesterol from the blood. This results in high levels of LDL cholesterol in the bloodstream. Choices A, B, and C are incorrect because they do not directly relate to the primary cause of primary hypercholesteremia.
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