ATI RN
ATI Pathophysiology Exam 2
1. Which of the following is the most likely indication for the use of immunosuppressant agents?
- A. Intractable seizure disorders
- B. Increased intracranial pressure
- C. Organ transplantation
- D. HIV/AIDS with multiple drug resistance
Correct answer: C
Rationale: The correct answer is C: Organ transplantation. Immunosuppressant agents are commonly used in organ transplant recipients to prevent organ rejection by suppressing the immune system. Choices A, B, and D are incorrect. Intractable seizure disorders are often managed with antiepileptic drugs, increased intracranial pressure is managed through various means like surgery and medications, and HIV/AIDS with multiple drug resistance is typically treated with antiretroviral therapy, not immunosuppressant agents.
2. The unique clinical presentation of a 3-month-old infant in the emergency department leads the care team to suspect botulism. Which assessment question posed to the parents is likely to be most useful in the differential diagnosis?
- A. Has your child received all recommended vaccinations?
- B. Has your child been feeding poorly or showing signs of constipation?
- C. Has your child been exposed to any sick individuals?
- D. Has your child been displaying signs of respiratory distress?
Correct answer: B
Rationale: The correct answer is B. Poor feeding and constipation are common early symptoms of infant botulism, which is caused by a neurotoxin that impairs muscle function. Option A is unrelated to the presentation of botulism. Option C does not directly relate to the symptoms of botulism. Option D is more indicative of respiratory issues rather than the constellation of symptoms seen in botulism.
3. A student nurse was asked which of the following best describes dementia. Which of the following best describes the condition?
- A. Memory loss as a natural consequence of aging
- B. Difficulty coping with physical and psychological changes
- C. Severe cognitive impairment that occurs rapidly
- D. Loss of cognitive abilities, impairing the ability to perform activities of daily living
Correct answer: D
Rationale: The correct answer is D. Dementia is characterized by a loss of cognitive abilities that impairs the individual's capacity to perform activities of daily living. Choice A is incorrect because dementia is not simply memory loss related to aging but involves broader cognitive deficits. Choice B is incorrect as it does not capture the comprehensive cognitive decline seen in dementia. Choice C is incorrect as dementia typically progresses gradually rather than rapidly, and it is not solely about severe cognitive impairment but also impacts daily functioning.
4. What is a cause of the crystallization within the synovial fluid of the joint affected by gouty arthritis?
- A. Destruction of proteoglycans
- B. Underexcretion of uric acid
- C. Overexcretion of uric acid
- D. Increased absorption of uric acid
Correct answer: B
Rationale: The correct answer is B: Underexcretion of uric acid. Gouty arthritis is primarily caused by the underexcretion of uric acid, leading to its accumulation in joints and subsequent crystallization. Choices A, C, and D are incorrect as they do not directly relate to the pathophysiology of gout. Destruction of proteoglycans, overexcretion of uric acid, and increased absorption of uric acid are not primary causes of gouty arthritis.
5. Which of the following are normal arterial blood gas values?
- A. PH 7.25, PaCO2 52 mm Hg, PaO2 75 mm Hg, HCO3 18 mEq/L
- B. PH 7.50, PaCO2 30 mm Hg, PaO2 80 mm Hg, HCO3 28 mEq/L
- C. PH 7.40, PaCO2 40 mm Hg, PaO2 90 mm Hg, HCO3 24 mEq/L
- D. PH 7.15, PaCO2 30 mm Hg, PaO2 50 mm Hg, HCO3 24 mEq/L
Correct answer: C
Rationale: The correct answer is C: PH 7.40, PaCO2 40 mm Hg, PaO2 90 mm Hg, HCO3 24 mEq/L. These values represent a balanced state for arterial blood gas. Choice A has lower than normal PH and HCO3 levels and higher PaCO2 and lower PaO2 levels. Choice B has higher than normal PH and HCO3 levels, lower PaCO2, and a normal PaO2 level. Choice D has a significantly lower PH and PaO2 level, normal HCO3 level, and low PaCO2 level, indicating an acidic state with impaired oxygenation.
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