ATI RN
ATI Pathophysiology Exam 2
1. Which of the following is the most likely indication for the use of immunosuppressant agents?
- A. Intractable seizure disorders
- B. Increased intracranial pressure
- C. Organ transplantation
- D. HIV/AIDS with multiple drug resistance
Correct answer: C
Rationale: The correct answer is C: Organ transplantation. Immunosuppressant agents are commonly used in organ transplant recipients to prevent organ rejection by suppressing the immune system. Choices A, B, and D are incorrect. Intractable seizure disorders are often managed with antiepileptic drugs, increased intracranial pressure is managed through various means like surgery and medications, and HIV/AIDS with multiple drug resistance is typically treated with antiretroviral therapy, not immunosuppressant agents.
2. Interpret the following arterial blood gas results: PH = 7.30; PaCO2 = 55 mmHg; HCO3 = 24 mEq/L
- A. Respiratory acidosis
- B. Metabolic acidosis
- C. Respiratory alkalosis
- D. Metabolic alkalosis
Correct answer: A
Rationale: The correct answer is A: Respiratory acidosis. In respiratory acidosis, there is an accumulation of CO2 in the blood, leading to a decrease in pH. The elevated PaCO2 of 55 mmHg in the given results indicates hypoventilation, causing respiratory acidosis. Choices B, C, and D are incorrect because the provided data does not show metabolic acidosis, respiratory alkalosis, or metabolic alkalosis.
3. What is the primary function of the kidneys in acid-base balance?
- A. The kidneys remove hydrogen ions and retain bicarbonate ions.
- B. The kidneys convert ammonia into urea, which is excreted in the urine.
- C. The kidneys produce aldosterone to regulate sodium levels.
- D. The kidneys secrete renin to regulate blood pressure.
Correct answer: A
Rationale: The correct answer is A. The kidneys are crucial in maintaining acid-base balance by removing hydrogen ions to decrease acidity and retaining bicarbonate ions to increase alkalinity. Choice B is incorrect because the conversion of ammonia into urea is related to nitrogen waste excretion, not acid-base balance. Choice C is incorrect as aldosterone regulates sodium levels, not acid-base balance. Choice D is also incorrect as renin is involved in regulating blood pressure, not acid-base balance.
4. Which of the following is a characteristic of the human immunodeficiency virus (HIV), which causes AIDS?
- A. HIV only infects B cells
- B. HIV is a retrovirus
- C. Infection does not require a host cell receptor
- D. After infection, cell death is immediate
Correct answer: B
Rationale: The correct answer is B. HIV is a retrovirus that infects T cells and leads to the gradual destruction of the immune system. Choice A is incorrect because HIV infects T cells primarily, not just B cells. Choice C is incorrect because HIV infection requires host cell receptors for entry. Choice D is incorrect because cell death after HIV infection is not immediate; instead, the virus gradually weakens the immune system over time.
5. A 30-year-old woman presents with joint pain, a malar rash, and photosensitivity. Which of the following is the most likely diagnosis?
- A. Rheumatoid arthritis
- B. Systemic lupus erythematosus
- C. Psoriatic arthritis
- D. Dermatomyositis
Correct answer: B
Rationale: The correct answer is B: Systemic lupus erythematosus. Joint pain, a malar rash, and photosensitivity are classic symptoms of systemic lupus erythematosus. Choice A, Rheumatoid arthritis, is incorrect as it typically presents with symmetric joint involvement and morning stiffness. Psoriatic arthritis (Choice C) is characterized by joint pain associated with psoriasis, which is not described in the case. Dermatomyositis (Choice D) presents with muscle weakness, skin rash, and elevated muscle enzymes, different from the symptoms presented in the case.
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