ATI RN
ATI Pharmacology Proctored
1. Which of the following drugs is associated with the reaction of Cinchonism?
- A. Valproic acid
- B. Quinidine
- C. Isoniazid
- D. Ethosuximide
Correct answer: B
Rationale: Cinchonism is associated with Quinidine, not Valproic acid, Isoniazid, or Ethosuximide. Cinchonism is characterized by symptoms such as tinnitus, dizziness, and headaches. Quinidine, being an antiarrhythmic agent, can lead to this condition as a side effect.
2. A healthcare provider is reviewing the health history of a client who is starting therapy with tamoxifen. The healthcare provider should recognize that tamoxifen is contraindicated in which of the following clients?
- A. A client with a history of deep-vein thrombosis
- B. A client with a history of migraine headaches
- C. A client with a history of hypertension
- D. A client with a history of anemia
Correct answer: A
Rationale: Tamoxifen is contraindicated in clients with a history of thromboembolic events, such as deep-vein thrombosis, due to the increased risk of blood clots. The estrogenic effects of tamoxifen can further increase the risk of thromboembolic events, making it unsafe for individuals with a history of deep-vein thrombosis. Choice B (migraine headaches), Choice C (hypertension), and Choice D (anemia) are not contraindications for tamoxifen therapy. Migraine headaches, hypertension, and anemia do not pose the same risk of adverse effects related to blood clot formation as deep-vein thrombosis does.
3. A client has a prescription for ceftriaxone. Which of the following information should the nurse include in the teaching?
- A. You may develop a cough while taking this medication.
- B. You should stop taking this medication if you develop a rash.
- C. This medication cannot be given orally.
- D. This medication may cause your urine to turn yellow.
Correct answer: B
Rationale: The correct answer is B. A rash can indicate an allergic reaction to ceftriaxone, which should be reported to the provider. It is crucial to instruct the client to discontinue the medication and seek medical attention if a rash develops to prevent potential serious adverse effects. Choices A, C, and D are incorrect because cough is not a common side effect of ceftriaxone, ceftriaxone is typically administered parenterally, and a yellow discoloration of urine is a harmless side effect due to the color of the medication itself, respectively.
4. A client with breast cancer is receiving cyclophosphamide. What finding should the nurse monitor for?
- A. Hypertension
- B. Hyperglycemia
- C. Ototoxicity
- D. Hemorrhagic cystitis
Correct answer: D
Rationale: When a client is receiving cyclophosphamide, the nurse should monitor for hemorrhagic cystitis, a severe adverse effect caused by bladder irritation. It is essential to watch for signs such as hematuria, dysuria, and urinary frequency, and promptly intervene to prevent further complications. Hypertension (Choice A) is not typically associated with cyclophosphamide use. Hyperglycemia (Choice B) is not a common side effect of cyclophosphamide. Ototoxicity (Choice C) is more commonly associated with medications like aminoglycoside antibiotics or high-dose aspirin.
5. A client has a new prescription for Ciprofloxacin. Which of the following instructions should the nurse include?
- A. Take this medication with meals.
- B. Avoid taking this medication with dairy products.
- C. Take this medication at bedtime.
- D. Increase your intake of potassium-rich foods.
Correct answer: B
Rationale: The correct answer is B: 'Avoid taking this medication with dairy products.' Ciprofloxacin should not be taken with dairy products because calcium can interfere with the absorption of the medication. Instructing the client to take it 1 hour before or 2 hours after consuming dairy products will ensure optimal effectiveness of the medication. Choice A is incorrect because Ciprofloxacin is usually recommended to be taken on an empty stomach or with a full glass of water. Choice C is incorrect as there is no specific requirement to take Ciprofloxacin at bedtime. Choice D is also incorrect as there is no need to increase intake of potassium-rich foods in relation to taking Ciprofloxacin.
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