what is the correct definition for absorption of a drug
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Nursing Elites

ATI RN

Proctored Pharmacology ATI

1. What is the correct definition of drug absorption?

Correct answer: A

Rationale: The correct definition of drug absorption is the movement of a drug from the site of administration into various tissues of the body. It is the process by which a drug is taken up and enters the systemic circulation. Choice B describes the pharmacokinetics of drugs, including absorption, distribution, metabolism, and excretion, but it is not a specific definition of drug absorption. Choice C is unrelated to drug absorption, as it refers to over-the-counter drugs. Choice D is too vague and does not specifically address the process of drug absorption.

2. A client with heart failure is receiving instructions about laxative use. The client should be advised to avoid which of the following laxatives?

Correct answer: A

Rationale: Clients with heart failure often have sodium restrictions. Sodium phosphate can lead to fluid retention due to sodium absorption, which is harmful for individuals with heart failure. Therefore, it should be avoided in this population to prevent exacerbating fluid overload. Psyllium, Bisacodyl, and Polyethylene glycol are safer options for individuals with heart failure as they do not pose the risk of exacerbating fluid overload through sodium retention.

3. A client with HIV is beginning therapy with zidovudine. The nurse should monitor the client for which of the following adverse effects of this medication?

Correct answer: A

Rationale: Fatigue is a common adverse effect of zidovudine due to its impact on bone marrow, leading to anemia. Zidovudine is known to suppress bone marrow function, resulting in decreased production of red blood cells and subsequently causing fatigue due to anemia. Monitoring for fatigue is essential to ensure early detection and management of this adverse effect.

4. A client has a new prescription for Labetalol. Which of the following instructions should be provided?

Correct answer: A

Rationale: The correct answer is A: Take the medication with food. Labetalol should be taken with food to increase absorption and reduce the risk of orthostatic hypotension. Taking it with food helps in better absorption and minimizes the potential drop in blood pressure when standing up, which can occur with this medication. Choice B is incorrect as Labetalol is not primarily associated with affecting blood glucose levels. Choice C is incorrect as Labetalol is a beta-blocker that would actually lower heart rate, not increase it. Choice D is incorrect because increasing intake of high-sodium foods could counteract the antihypertensive effects of Labetalol.

5. A client has a new prescription for Methotrexate to treat Rheumatoid Arthritis. Which of the following instructions should the nurse provide?

Correct answer: C

Rationale: The correct instruction for a client taking Methotrexate is to avoid alcohol, as it can increase the risk of liver damage. Alcohol consumption should be avoided to prevent potential adverse effects while on this medication.

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