ATI RN
ATI Pathophysiology Exam 3
1. What is reperfusion injury?
- A. Healing bone tissue after fracture
- B. Skin wound tunneling and shear
- C. Secondary injury after reestablishing blood flow
- D. Injury after blood transfusion
Correct answer: C
Rationale: Reperfusion injury refers to the secondary injury that occurs after blood flow is reestablished following ischemia. This process leads to tissue damage due to the sudden reintroduction of oxygen and nutrients, causing oxidative stress, inflammation, and cell death. Choice A is incorrect as it describes the normal healing process of bone tissue after a fracture. Choice B is incorrect as it describes specific mechanisms related to skin wounds, not reperfusion injury. Choice D is incorrect as it refers to a different concept, which is adverse reactions or complications that can occur after a blood transfusion, not reperfusion injury.
2. A patient is admitted to the emergency room and is found to have proteinuria, a low serum albumin level, edema, and elevated blood lipids. Which condition do these symptoms typically associate with?
- A. Nephrotic syndrome
- B. Acute kidney injury
- C. Rejection of a kidney transplant
- D. Renal colic
Correct answer: A: Nephrotic syndrome
Rationale: The correct answer is A: Nephrotic syndrome. Nephrotic syndrome is characterized by proteinuria (excess protein in urine), hypoalbuminemia (low serum albumin), edema (swelling due to fluid buildup), and hyperlipidemia (elevated blood lipids). These symptoms occur as a result of damage to the kidneys' filtering units. Acute kidney injury, rejection of a kidney transplant, and renal colic do not present with the same combination of symptoms as nephrotic syndrome. Acute kidney injury typically presents with a sudden decrease in kidney function, resulting in a build-up of waste products in the blood. Rejection of a kidney transplant may present with fever, pain at the transplant site, and changes in urine output. Renal colic usually presents with intense pain in the lower back or side, related to kidney stones.
3. What is the primary concern in a patient with a low CD4 T-cell count in HIV?
- A. Increased risk of infection
- B. Increased risk of bleeding
- C. Decreased immunity leading to opportunistic infections
- D. Increased risk of cardiac complications
Correct answer: A
Rationale: The correct answer is A: Increased risk of infection. In HIV patients with a low CD4 T-cell count, the primary concern is the increased susceptibility to infections due to compromised immunity. This compromised immune system can lead to various infections, making infection control crucial. Choice B, increased risk of bleeding, is not directly associated with a low CD4 count in HIV. Option C, decreased immunity leading to opportunistic infections, conveys a similar concern as the correct answer but lacks specificity. Choice D, increased risk of cardiac complications, is not typically the primary concern in HIV patients with a low CD4 count, as infections and opportunistic diseases pose more immediate threats to health.
4. What are the expected symptoms in a patient with a thrombotic stroke?
- A. Gradual loss of function on one side of the body
- B. Sudden loss of consciousness
- C. Severe headache and confusion
- D. Loss of sensation in the affected limb
Correct answer: A
Rationale: A thrombotic stroke typically presents with a gradual loss of function on one side of the body. This gradual onset distinguishes it from a hemorrhagic stroke, which often manifests with sudden and severe symptoms like loss of consciousness (choice B), severe headache and confusion (choice C), or loss of sensation in the affected limb (choice D). Therefore, choices B, C, and D are not typically associated with thrombotic strokes.
5. Which of the following laboratory results would be expected in a client with peritonitis?
- A. Partial thromboplastin time above 100 seconds
- B. Hemoglobin level below 10 mg/dL
- C. Potassium level above 5.5 mEq/L
- D. White blood cell count above 15,000
Correct answer: D
Rationale: A white blood cell count above 15,000 is indicative of an infection, such as peritonitis.
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