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MSN 570 Advanced Pathophysiology Final 2024
1. Which of the following are manifestations of Cushing syndrome?
- A. Truncal obesity with thin extremities.
- B. Enlargement of face, hands, and feet.
- C. Cachexia.
- D. Thick scalp hair.
Correct answer: A
Rationale: Truncal obesity with thin extremities is a classic manifestation of Cushing syndrome due to the redistribution of fat. Enlargement of face, hands, and feet is seen in conditions like acromegaly, not Cushing syndrome. Cachexia is a state of severe weight loss and muscle wasting, typically seen in conditions like cancer or advanced infections. Thick scalp hair is not typically associated with Cushing syndrome.
2. Which of the following is a common cause of mechanical small intestine obstruction?
- A. Infection
- B. Postoperative adhesions
- C. Tumors
- D. Foreign body
Correct answer: B
Rationale: Postoperative adhesions are a common cause of mechanical small intestine obstruction. Adhesions can form after abdominal surgery, causing bands of scar tissue that may twist or pull the intestines, leading to obstruction. This is a more common cause compared to infection, tumors, or foreign bodies. Infection may lead to inflammation but is not a typical cause of mechanical obstruction. Tumors and foreign bodies can cause blockages but are less common than postoperative adhesions.
3. A patient is prescribed finasteride (Proscar) for benign prostatic hyperplasia (BPH). What should the nurse include in the patient teaching regarding the expected outcomes of this therapy?
- A. The medication will cure BPH after treatment is complete.
- B. The effects of the medication may take several weeks or months to become noticeable.
- C. The medication may cause increased hair growth.
- D. The medication may decrease libido.
Correct answer: B
Rationale: The correct answer is B. The effects of finasteride in treating BPH may take several weeks or months to become noticeable, so patients should be informed about this expected time frame. Choice A is incorrect because finasteride does not cure BPH but helps manage symptoms. Choice C is incorrect as increased hair growth is a side effect of finasteride, not an expected outcome for BPH treatment. Choice D is also incorrect as decreased libido is a potential side effect of finasteride, not an expected outcome for BPH treatment.
4. DiGeorge syndrome is a primary immune deficiency caused by:
- A. Failure of B cells to mature
- B. Congenital lack of thymic tissue
- C. Failure of formed elements of blood to develop
- D. Selective IgG deficiency
Correct answer: B
Rationale: DiGeorge syndrome is caused by a congenital lack of thymic tissue, which plays a crucial role in T cell development and maturation, leading to immune deficiency. Choice A is incorrect because DiGeorge syndrome primarily affects T cells, not B cells. Choice C is incorrect as it is too broad and not specific to the thymus. Choice D is incorrect as selective IgG deficiency is a different condition unrelated to DiGeorge syndrome.
5. In Guillain-Barre syndrome, what pathophysiologic process underlies the deficits that accompany the degeneration of myelin in the peripheral nervous system (PNS)?
- A. The destruction of myelin results in a reduction in Schwann cell production in the client's PNS.
- B. The lack of myelin surrounding nerve cells compromises the axonal transport system.
- C. Without remyelination, the axon will eventually die.
- D. A deficit of myelin makes the client more susceptible to infection by potential pathogens.
Correct answer: C
Rationale: In Guillain-Barre syndrome, the destruction of myelin leads to axonal damage. If remyelination does not occur, the axon will eventually degenerate and die, impacting nerve function. Choice A is incorrect because the destruction of myelin does not affect Schwann cell production. Choice B is incorrect as the lack of myelin directly affects the conduction of nerve impulses, not the axonal transport system. Choice D is incorrect as a deficit of myelin does not predispose the client to infections by potential pathogens.
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