ATI RN
Pathophysiology Final Exam
1. A female patient is concerned about the side effects of hormone replacement therapy (HRT). What common side effect should the nurse explain?
- A. Weight gain
- B. Hair loss
- C. Increased libido
- D. Decreased energy levels
Correct answer: A
Rationale: The correct answer is A: Weight gain. Weight gain is a common side effect of hormone replacement therapy (HRT) due to hormonal changes. Patients should be informed about this possibility as part of their treatment plan. Hair loss (Choice B) is not a common side effect of HRT. Increased libido (Choice C) and decreased energy levels (Choice D) are not typically associated with HRT side effects. Therefore, the nurse should focus on discussing weight gain with the patient.
2. A patient is being administered chemotherapeutic agents for the treatment of cancer. Which of the following blood cells will be stimulated by the colony-stimulating factors in response to the effects of the chemotherapy?
- A. White blood cells
- B. Red blood cells
- C. Phagocytes
- D. Myocardial cells
Correct answer: A
Rationale: The correct answer is White blood cells. Colony-stimulating factors stimulate the production of white blood cells in response to the effects of chemotherapy, as it can lead to myelosuppression. Red blood cells are not directly stimulated by colony-stimulating factors. Phagocytes are a type of white blood cell involved in immune responses, but they are not specifically stimulated by colony-stimulating factors. Myocardial cells are cardiac muscle cells and are not directly involved in the response to chemotherapy-induced myelosuppression.
3. On the advice of his brother, a 53-year-old man has made an appointment to request a prescription for Viagra. The nurse who works at the clinic is reviewing the man's medical history and would recognize what health problem as being prohibitive to this treatment?
- A. Type 2 diabetes, treated with metformin
- B. Hypercholesterolemia, treated with simvastatin
- C. Angina, treated with nitroglycerin
- D. Hypertension, treated with metoprolol
Correct answer: C
Rationale: Nitroglycerin is contraindicated with Viagra due to their combined effects on lowering blood pressure, which can result in a severe drop and potentially life-threatening complications. Using both medications together can lead to hypotension, putting the patient at risk. Therefore, the presence of angina treated with nitroglycerin would make prescribing Viagra unsafe. Choices A, B, and D are not directly contraindicated with Viagra and can be managed concurrently with this treatment.
4. Which of the following would the nurse expect to see in a client experiencing hypoventilation?
- A. Increased oxygenation in the alveoli
- B. Increased carbon dioxide in the bloodstream
- C. Decreased hemoglobin in the bloodstream
- D. Decreased carbon dioxide in the alveoli
Correct answer: B
Rationale: In hypoventilation, there is inadequate ventilation leading to decreased removal of carbon dioxide. This results in increased carbon dioxide in the bloodstream. The other choices are incorrect because hypoventilation does not improve oxygenation in the alveoli (Choice A), decrease hemoglobin in the bloodstream (Choice C), or decrease carbon dioxide in the alveoli (Choice D).
5. A client with a diagnosis of depression has been prescribed a medication that ultimately increases the levels of the neurotransmitter serotonin between neurons. Which process will accompany the actions of the neurotransmitter in a chemical synapse?
- A. Two-way communication between neurons is permitted, in contrast to the one-way communication in electrical synapses.
- B. Communication between a neuron and the single neuron it is connected with will be facilitated.
- C. The neurotransmitter will cross gap junctions more readily.
- D. More neurotransmitters will cross the synaptic cleft and bond with postsynaptic receptors.
Correct answer: D
Rationale: When serotonin levels increase, more neurotransmitters will cross the synaptic cleft and bind with postsynaptic receptors, facilitating enhanced communication. Option A is incorrect because chemical synapses, unlike electrical synapses, are unidirectional. Option B is incorrect because neurotransmitters impact communication with multiple neurons, not just a single connected neuron. Option C is incorrect because neurotransmitters cross the synaptic cleft, not gap junctions.
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