ATI RN
ATI Proctored Pharmacology 2023
1. What is pharmacodynamics?
- A. The medical reference summarizing standards of drug purity, strength, and directions for synthesis
- B. The drug's actions at receptor sites and the physiological, chemical, and behavioral effects produced by these actions
- C. The maximum response that a drug can produce
- D. Movements of the drugs throughout the body
Correct answer: B
Rationale: Pharmacodynamics refers to the drug's actions at receptor sites and the physiological, chemical, and behavioral effects produced by these actions. It involves understanding how drugs interact with the body at the molecular level to produce their effects, including mechanisms of action, receptor binding, and downstream physiological responses. Choice A is incorrect because it describes pharmacopeia, which is a reference book containing standards for drugs. Choice C refers to efficacy, which is the maximum effect a drug can produce. Choice D describes pharmacokinetics, which focuses on the movement of drugs within the body.
2. When teaching a client who has a new prescription for Ciprofloxacin, which of the following instructions should the nurse include?
- A. Take this medication with an antacid.
- B. Avoid direct sunlight.
- C. Increase your intake of dairy products.
- D. Expect urine to turn orange.
Correct answer: B
Rationale: The correct instruction for a client prescribed Ciprofloxacin is to avoid direct sunlight. Ciprofloxacin can cause photosensitivity, increasing the risk of sunburn. Clients should be advised to avoid direct sunlight and wear protective clothing, including hats and sunglasses when going outdoors to prevent skin damage. Choices A, C, and D are incorrect. Taking Ciprofloxacin with an antacid can reduce its absorption, so they should not be taken together. Increasing dairy product intake is not necessary or relevant to taking Ciprofloxacin. While Ciprofloxacin can discolor urine, turning it orange, this is not a critical side effect that requires specific instructions for the client.
3. A client has a new prescription for Prednisone and is receiving discharge instructions. Which of the following dietary instructions should the nurse include?
- A. Increase your intake of potassium-rich foods.
- B. Increase your intake of dairy products.
- C. Avoid foods high in vitamin K.
- D. Decrease your intake of protein.
Correct answer: A
Rationale: The correct answer is to increase the intake of potassium-rich foods. Prednisone can lead to potassium depletion; therefore, it is essential for clients to consume foods high in potassium such as bananas, oranges, and spinach to counteract this effect and maintain electrolyte balance. Choice B is incorrect because increasing dairy products is not directly related to the side effects of Prednisone. Choice C is incorrect because avoiding foods high in vitamin K is more relevant for clients on anticoagulants. Choice D is incorrect because decreasing protein intake is not a typical dietary instruction for clients prescribed Prednisone.
4. A staff educator is reviewing medication dosages and factors that influence medication metabolism with a group of nurses at an in-service presentation. Which of the following factors should the educator include as a reason to administer lower medication dosages? (Select all that apply.)
- A. Increased renal secretion
- B. Increased medication-metabolizing enzymes
- C. Liver failure
- D. Peripheral vascular disease
Correct answer: C
Rationale: Liver failure impairs metabolism, leading to increased medication concentrations. When liver function is compromised, lower dosages are necessary to prevent adverse effects. Increased renal secretion is not a reason for lower medication dosages, as it primarily affects excretion rather than metabolism. Increased medication-metabolizing enzymes would usually require higher dosages to achieve the desired effect. Peripheral vascular disease does not directly impact medication metabolism or dosage requirements.
5. The healthcare professional is preparing to administer atenolol (Tenormin) to a client with angina. Which vital sign would cause the healthcare professional to question administering this drug?
- A. Respirations 12 breaths per minute
- B. Pulse 52 beats per minute
- C. Blood pressure 134/72
- D. Oxygen saturation 95%
Correct answer: B
Rationale: Atenolol is a beta-blocker medication that can lower heart rate. A pulse of 52 beats per minute is relatively low and administering atenolol could further decrease the heart rate, potentially leading to bradycardia. Monitoring the pulse rate and holding the medication if the pulse is below the prescribed parameters is crucial to prevent adverse effects such as bradycardia and hypotension.
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