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ATI Pharmacology Test Bank
1. What is one of the therapeutic uses of Valproate?
- A. Suppression of seizure activity
- B. Replacement of hypothyroidism to restore normal hormone balance
- C. Maintenance of blood glucose
- D. Lowering of blood pressure
Correct answer: A
Rationale: Valproate, also known as Valproic acid, is commonly used in medicine for the suppression of seizure activity. It is an anticonvulsant medication that helps manage and prevent seizures in various conditions such as epilepsy. While it is not used for replacing hypothyroidism, maintaining blood glucose levels, or lowering blood pressure, its primary therapeutic use is in managing seizures.
2. A client has a new prescription for Loperamide. Which of the following instructions should the nurse include?
- A. Take the medication with a full glass of water.
- B. Avoid activities that require alertness.
- C. Increase your intake of high-fiber foods.
- D. Expect your stools to be black and tarry.
Correct answer: B
Rationale: The correct answer is B. Loperamide can cause drowsiness and dizziness, so clients should avoid activities that require alertness until they know how the medication affects them. Taking the medication with a full glass of water can help with absorption. Increasing intake of high-fiber foods is not directly related to Loperamide. Black, tarry stools are not expected side effects of this medication, so informing the client to expect this is incorrect.
3. A healthcare provider is assessing a client who is taking levothyroxine. The healthcare provider should recognize that which of the following findings is a manifestation of levothyroxine overdose?
- A. Insomnia
- B. Constipation
- C. Drowsiness
- D. Hypoactive deep-tendon reflexes
Correct answer: A
Rationale: Insomnia is a common symptom of levothyroxine overdose due to excessive stimulation of the central nervous system. Levothyroxine is a thyroid hormone replacement medication, and an overdose can lead to hyperthyroidism symptoms, including insomnia. Constipation and drowsiness are not typically associated with levothyroxine overdose. Hypoactive deep-tendon reflexes are more indicative of hypothyroidism rather than an overdose of levothyroxine.
4. A client has a new prescription for Cyclobenzaprine to treat muscle spasms. Which of the following instructions should the nurse include in the teaching?
- A. Avoid driving or operating heavy machinery while taking this medication.
- B. Take this medication on an empty stomach for best results.
- C. Take this medication only when experiencing muscle pain.
- D. Increase your intake of potassium-rich foods while taking this medication.
Correct answer: A
Rationale: The correct instruction that the nurse should include in the teaching for a client prescribed Cyclobenzaprine is to avoid driving or operating heavy machinery while taking this medication. Cyclobenzaprine can cause drowsiness, so it is important to advise clients to avoid activities that require alertness and coordination to prevent accidents or injuries. Choice B is incorrect because Cyclobenzaprine can be taken with or without food. Choice C is incorrect because Cyclobenzaprine is typically taken regularly as prescribed, not just when experiencing muscle pain. Choice D is incorrect because there is no specific need to increase potassium-rich foods while taking Cyclobenzaprine.
5. During an admission assessment for a client with severe Aspirin toxicity, what finding should the nurse expect?
- A. Body temperature 35°C (95°F)
- B. Lung crackles
- C. Cool, dry skin
- D. Respiratory depression
Correct answer: D
Rationale: In severe Aspirin toxicity, respiratory depression can occur due to increasing respiratory acidosis. Aspirin toxicity leads to metabolic acidosis, stimulating the respiratory center in the brain to increase the respiratory rate initially. However, as the toxicity worsens, respiratory muscle fatigue and depression can occur, resulting in respiratory depression. This can lead to hypoxia, respiratory failure, and ultimately, respiratory arrest.
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