Nursing Elites

1. Which medication is contraindicated with Nitroglycerin?

• A. Hydrochloroquine
• B. Methylprednisolone
• C. Phenazopyridine
• D. Erectile dysfunction drugs

Correct answer: D

Rationale: The correct answer is D: Erectile dysfunction drugs. Erectile dysfunction drugs are contraindicated with Nitroglycerin because they can potentiate the hypotensive effects of Nitroglycerin, leading to severe hypotension. Choices A, B, and C are incorrect because they are not known to have significant interactions with Nitroglycerin.

2. A client is taking Furosemide for heart failure. Which of the following laboratory tests should the nurse monitor to assess for an adverse effect of this medication?

• A. Serum potassium.
• B. Serum calcium.
• C. Serum sodium.
• D. Serum magnesium.

Correct answer: A

Rationale: Furosemide, a loop diuretic commonly used in heart failure, can cause hypokalemia (low potassium levels) as a side effect. Monitoring serum potassium levels is crucial to detect and prevent complications associated with low potassium levels, such as cardiac arrhythmias. Therefore, the nurse should prioritize assessing the client's serum potassium levels regularly while on Furosemide. Serum calcium, sodium, and magnesium levels are not typically affected by Furosemide and are not the primary focus of monitoring for adverse effects of this medication.

3. Which drug undergoes extensive first-pass hepatic metabolism?

• A. Heparin
• B. Insulin
• C. Propranolol
• D. Nitroglycerin

Correct answer: C

Rationale: Propranolol undergoes extensive first-pass hepatic metabolism in the liver. When administered orally, propranolol is extensively metabolized by the liver before reaching systemic circulation, leading to reduced bioavailability. This process is known as first-pass hepatic metabolism, which significantly affects the drug's effectiveness and necessitates higher oral doses compared to other routes of administration. Heparin (Choice A) is not metabolized by the liver but excreted unchanged by the kidneys. Insulin (Choice B) is a peptide hormone that is not subject to significant first-pass metabolism. Nitroglycerin (Choice D) is primarily metabolized in the blood and tissues, bypassing significant first-pass metabolism in the liver.

4. A client has a new prescription for Lisinopril. Which of the following laboratory values should be monitored?

• A. Serum potassium
• B. Serum sodium
• C. Serum calcium
• D. Serum magnesium

Correct answer: A

Rationale: Corrected Rationale: Lisinopril is an ACE inhibitor that can cause hyperkalemia by reducing potassium excretion through the kidneys. Monitoring serum potassium levels is crucial to detect hyperkalemia early and prevent adverse effects such as cardiac arrhythmias. Choices B, C, and D are incorrect because Lisinopril is not known to significantly impact sodium, calcium, or magnesium levels in the same way it affects potassium levels.

5. A client has a new prescription for Furosemide. Which of the following instructions should the nurse include?

• A. Take this medication at bedtime.
• B. Avoid eating foods high in potassium.
• C. Change positions slowly.
• D. Take this medication with meals.

Correct answer: C

Rationale: The correct instruction to include when a client is prescribed Furosemide is to change positions slowly. Furosemide is a diuretic that can lead to orthostatic hypotension, causing dizziness and increasing the risk of falls. By advising the client to change positions slowly, the nurse helps prevent these adverse effects and ensures the client's safety. Option A is incorrect because Furosemide is usually taken in the morning to prevent disturbed sleep due to frequent urination. Option B is incorrect as Furosemide can cause potassium loss, so advising to avoid foods high in potassium would not be appropriate. Option D is incorrect because taking Furosemide with meals may increase the risk of side effects and decrease its effectiveness.

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