ATI RN
ATI Pharmacology Test Bank
1. A client has a prescription for Trimethoprim-Sulfamethoxazole. Which of the following instructions should the nurse include?
- A. Take the medication with food.
- B. Increase fluid intake.
- C. Expect reddish-orange urine.
- D. Avoid high-protein foods.
Correct answer: B
Rationale: The correct instruction for a client prescribed Trimethoprim-Sulfamethoxazole is to increase fluid intake. This helps prevent crystalluria and kidney stones, which are potential adverse effects of this medication. Adequate hydration is essential to reduce the risk of these complications.
2. What finding should a nurse monitor for as an adverse effect when a client has a new prescription for Spironolactone?
- A. Hyperkalemia
- B. Hypoglycemia
- C. Hypocalcemia
- D. Hyponatremia
Correct answer: A
Rationale: The correct answer is hyperkalemia. Spironolactone is a potassium-sparing diuretic that can lead to an increase in potassium levels. Hyperkalemia can be dangerous, causing muscle weakness and cardiac dysrhythmias. Monitoring potassium levels closely is crucial when a client is on Spironolactone. Hypoglycemia (choice B) is incorrect because Spironolactone does not typically affect blood glucose levels. Hypocalcemia (choice C) and hyponatremia (choice D) are also incorrect as Spironolactone's primary impact is on potassium levels.
3. When teaching a client who has a new prescription for Dextromethorphan to suppress a cough, which adverse effect should the nurse instruct the client to monitor for?
- A. Diarrhea
- B. Anxiety
- C. Sedation
- D. Palpitations
Correct answer: C
Rationale: The correct answer is C: Sedation. Dextromethorphan can cause sedation, so the client should be advised to avoid activities that require alertness. Diarrhea, anxiety, and palpitations are not commonly associated adverse effects of Dextromethorphan.
4. A client has a new prescription for Trimethoprim-sulfamethoxazole. Which of the following information should the nurse include?
- A. Take the medication on an empty stomach.
- B. Maintain a fluid restriction while taking it.
- C. Take it with food.
- D. Stop taking it when manifestations subside.
Correct answer: C
Rationale: The correct answer is C: 'Take it with food.' Trimethoprim-sulfamethoxazole can cause gastrointestinal upset, and taking it with food helps reduce the risk of stomach irritation. It should not be taken on an empty stomach. Maintaining good hydration is important to prevent kidney-related side effects, so maintaining a fluid restriction, as in choice B, is not appropriate. Additionally, stopping the medication when manifestations subside, as in choice D, is incorrect as antibiotics should be taken for the full prescribed course to ensure eradication of the infection and to prevent antibiotic resistance.
5. Which of the following is not a side effect of loop diuretics?
- A. Alkalosis
- B. Nausea
- C. Hypotension
- D. Potassium deficits
Correct answer: B
Rationale: Nausea is not commonly associated with loop diuretics. Loop diuretics are known to cause electrolyte imbalances such as potassium deficits, metabolic alkalosis, and hypotension due to excessive fluid loss. Nausea is not a typical side effect of loop diuretics.
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