ATI RN
ATI Pharmacology
1. A healthcare provider is providing discharge instructions to a client who is prescribed Prednisone. Which of the following dietary instructions should the healthcare provider include?
- A. Increase your intake of potassium-rich foods.
- B. Increase your intake of dairy products.
- C. Avoid foods high in vitamin K.
- D. Decrease your intake of protein.
Correct answer: A
Rationale: The correct answer is to increase the intake of potassium-rich foods (Choice A). Prednisone can cause potassium depletion, so clients should increase their intake of foods such as bananas, oranges, and spinach. Potassium-rich foods help maintain electrolyte balance and prevent complications associated with low potassium levels, such as muscle weakness and irregular heartbeats. Choices B, C, and D are incorrect because increasing dairy products (Choice B) or avoiding foods high in vitamin K (Choice C) are not specifically related to Prednisone therapy. Decreasing protein intake (Choice D) is also not necessary in this case.
2. A client with Hodgkin's disease is receiving Cyclophosphamide IV. Which medication should be administered concurrently to prevent an adverse effect of Cyclophosphamide?
- A. Uroprotectant agent, such as mesna
- B. Opioid, such as morphine
- C. Loop diuretic, such as furosemide
- D. H1 receptor antagonist, such as diphenhydramine
Correct answer: A
Rationale: Mesna, an uroprotectant agent, is administered with nitrogen mustard chemotherapy drugs like Cyclophosphamide to prevent hemorrhagic cystitis, a common adverse effect. Mesna works by binding to and inactivating the toxic metabolites of Cyclophosphamide in the bladder, thereby reducing the risk of bladder toxicity.
3. A client in the post-anesthesia recovery unit received a nondepolarizing neuromuscular blocking agent and is experiencing muscle weakness. The nurse should anticipate a prescription for which of the following medications?
- A. Neostigmine
- B. Naloxone
- C. Dantrolene
- D. Vecuronium
Correct answer: A
Rationale: Neostigmine is a cholinesterase inhibitor commonly used to reverse the effects of nondepolarizing neuromuscular blockers by increasing acetylcholine levels at the neuromuscular junction, thereby helping to restore muscle strength. Naloxone is an opioid antagonist used to reverse opioid effects, not neuromuscular blockade. Dantrolene is a skeletal muscle relaxant used to treat malignant hyperthermia or neuroleptic malignant syndrome, not to reverse neuromuscular blockade. Vecuronium is a nondepolarizing neuromuscular blocking agent, like the one the client received, and is not used to reverse its effects.
4. A healthcare professional is reviewing a client's medication history and notes a new prescription for Enalapril. The healthcare professional should monitor the client for which of the following as an adverse effect of this medication?
- A. Bradycardia
- B. Hyperkalemia
- C. Hypoglycemia
- D. Hypocalcemia
Correct answer: B
Rationale: Enalapril, an ACE inhibitor, can cause hyperkalemia as an adverse effect due to decreased aldosterone levels, which leads to potassium retention. Monitoring potassium levels is essential to prevent potential complications associated with hyperkalemia. The other options, bradycardia, hypoglycemia, and hypocalcemia, are not typically associated with Enalapril use and are less likely to occur as adverse effects.
5. A client has a new prescription for Timolol. How should the nurse instruct the client to insert eye drops?
- A. Press your finger on the inside corner of your eye for 1 minute after application.
- B. Apply the eye drops directly to the cornea.
- C. Drop the prescribed amount of medication into the center of the conjunctival sac.
- D. Wipe your eyes gently with a tissue immediately after application.
Correct answer: C
Rationale: When administering eye drops, it is essential to instruct the client to drop the prescribed amount of medication into the center of the conjunctival sac. This technique helps ensure proper distribution of the medication and reduces the risk of potential adverse effects. Pressing on the inside corner of the eye is done to prevent systemic absorption, applying drops directly to the cornea can cause irritation, and wiping the eyes after application can lead to decreased effectiveness of the medication.
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