ATI RN
ATI Pharmacology
1. A client is receiving daily doses of Oprelvekin. Which of the following laboratory values should be monitored to determine the effectiveness of this medication?
- A. Hemoglobin
- B. Absolute neutrophil count
- C. Platelet count
- D. Total white blood cell count
Correct answer: C
Rationale: Oprelvekin is a medication that stimulates platelet production. Therefore, monitoring the platelet count is essential to assess the effectiveness of this drug. The expected outcome for oprelvekin therapy is a platelet count greater than 50,000/mm^3. Changes in platelet count can indicate the response to the medication and help in adjusting the treatment plan accordingly. Monitoring hemoglobin, absolute neutrophil count, or total white blood cell count is not directly related to the mechanism of action of Oprelvekin and therefore would not provide accurate information on the drug's effectiveness.
2. A client has a new prescription for Lisinopril. Which of the following instructions should the nurse include?
- A. Avoid salt substitutes.
- B. Take this medication at bedtime.
- C. Increase your intake of potassium-rich foods.
- D. Take this medication with food.
Correct answer: A
Rationale: The correct instruction for a client prescribed Lisinopril is to avoid salt substitutes. Lisinopril, an ACE inhibitor, can lead to hyperkalemia, hence the importance of avoiding salt substitutes that may contain potassium. Instructing the client to avoid salt substitutes helps prevent potential adverse effects of increased potassium levels.
3. A client has a new prescription for Efavirenz, an NNRTI. Which of the following instructions should the nurse include?
- A. Take this medication at bedtime to prevent drowsiness.
- B. Take this medication with a glass of milk.
- C. Take this medication with a glass of juice.
- D. Take this medication at the same time every day.
Correct answer: A
Rationale: The correct instruction is to take Efavirenz at bedtime to prevent drowsiness and manage central nervous system side effects like dizziness and vivid dreams. While it is important to take the medication at the same time daily for consistent blood levels, the emphasis should be on bedtime to minimize the impact of these side effects. Choices B and C suggesting taking the medication with milk or juice are incorrect and not relevant to optimizing Efavirenz therapy.
4. A client has a new prescription for Hydrochlorothiazide. Which of the following adverse effects should the nurse monitor?
- A. Hyponatremia
- B. Hyperkalemia
- C. Hypercalcemia
- D. Hypoglycemia
Correct answer: A
Rationale: Corrected Rationale: Hydrochlorothiazide, a diuretic, can lead to electrolyte imbalances, particularly hyponatremia (low sodium levels). The nurse should closely monitor the client's sodium levels due to the potential adverse effect of Hydrochlorothiazide. Incorrect Rationales: - Hyperkalemia (Choice B) is less likely to be caused by Hydrochlorothiazide; in fact, it can lead to hypokalemia. - Hypercalcemia (Choice C) is not a common adverse effect of Hydrochlorothiazide. - Hypoglycemia (Choice D) is not directly associated with Hydrochlorothiazide use.
5. A client has a new prescription for alendronate to treat osteoporosis. Which of the following instructions should be included?
- A. Take the medication with food to reduce nausea.
- B. Take the medication first thing in the morning on an empty stomach.
- C. Take the medication with a full glass of milk.
- D. Take the medication with meals.
Correct answer: B
Rationale: Alendronate should be taken first thing in the morning on an empty stomach to maximize absorption. Taking it with food, milk, or meals can reduce its effectiveness by impairing absorption. Therefore, advising the client to take it on an empty stomach is crucial for optimal therapeutic outcomes.
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