a nurse is caring for a client who is receiving daily doses of oprelvekin which of the following laboratory values should the nurse monitor to determi

ATI RN

ATI Pharmacology

1. A client is receiving daily doses of Oprelvekin. Which of the following laboratory values should be monitored to determine the effectiveness of this medication?

A. Hemoglobin
B. Absolute neutrophil count
C. Platelet count
D. Total white blood cell count

Correct answer: C

Rationale: Oprelvekin is a medication that stimulates platelet production. Therefore, monitoring the platelet count is essential to assess the effectiveness of this drug. The expected outcome for oprelvekin therapy is a platelet count greater than 50,000/mm^3. Changes in platelet count can indicate the response to the medication and help in adjusting the treatment plan accordingly. Monitoring hemoglobin, absolute neutrophil count, or total white blood cell count is not directly related to the mechanism of action of Oprelvekin and therefore would not provide accurate information on the drug's effectiveness.

2. Which medication is contraindicated with Nitroglycerin?

A. Hydrochloroquine
B. Methylprednisolone
C. Phenazopyridine
D. Erectile dysfunction drugs

Correct answer: D

Rationale: The correct answer is D: Erectile dysfunction drugs. Erectile dysfunction drugs are contraindicated with Nitroglycerin because they can potentiate the hypotensive effects of Nitroglycerin, leading to severe hypotension. Choices A, B, and C are incorrect because they are not known to have significant interactions with Nitroglycerin.

3. During an admission assessment for a client with severe Aspirin toxicity, which finding should the nurse expect?

A. Body temperature 35°C (95°F)
B. Lung crackles
C. Cool, dry skin
D. Respiratory depression

Correct answer: D

Rationale: In severe Aspirin toxicity, respiratory depression is an anticipated finding due to the development of respiratory acidosis. Aspirin toxicity can lead to metabolic acidosis, causing the individual to hyperventilate initially to compensate. However, as the condition progresses, respiratory depression can occur, resulting in impaired gas exchange and respiratory acidosis.

4. When teaching a client with a prescription for Vancomycin, which instruction should the nurse include?

A. Expect red man syndrome during treatment.
B. Take the medication with a full glass of water.
C. Increase your intake of potassium-rich foods.
D. Monitor for hearing loss while taking this medication.

Correct answer: D

Rationale: The correct answer is D. Vancomycin is known to cause ototoxicity, which can result in hearing loss. Therefore, it is important for clients to monitor for any changes in their hearing while taking this medication and promptly report any issues to their healthcare provider for further evaluation and management. Choices A, B, and C are incorrect because red man syndrome is associated with rapid infusion of Vancomycin, not a common side effect during treatment; taking the medication with a full glass of water is a general instruction for many medications but not specific to Vancomycin; and increasing potassium-rich foods is not directly related to Vancomycin therapy.

5. Which of the following is not a side effect of Sympathoplegics (Clonidine)?

A. Hypertension
B. Difficulty breathing
C. Dry oral cavity
D. Lethargic behavior

Correct answer: A

Rationale: The correct answer is A. Clonidine, a Sympathoplegic, typically causes hypotension rather than hypertension. The other side effects associated with Clonidine include dry oral cavity, lethargic behavior, and difficulty breathing, making them incorrect choices in this context.