ATI RN
ATI Pharmacology
1. A client is receiving daily doses of Oprelvekin. Which of the following laboratory values should be monitored to determine the effectiveness of this medication?
- A. Hemoglobin
- B. Absolute neutrophil count
- C. Platelet count
- D. Total white blood cell count
Correct answer: C
Rationale: Oprelvekin is a medication that stimulates platelet production. Therefore, monitoring the platelet count is essential to assess the effectiveness of this drug. The expected outcome for oprelvekin therapy is a platelet count greater than 50,000/mm^3. Changes in platelet count can indicate the response to the medication and help in adjusting the treatment plan accordingly. Monitoring hemoglobin, absolute neutrophil count, or total white blood cell count is not directly related to the mechanism of action of Oprelvekin and therefore would not provide accurate information on the drug's effectiveness.
2. A patient with hypertension is taking an ACE inhibitor to lower blood pressure. What should the nurse advise the patient to avoid in their diet?
- A. Vinegar
- B. Apples
- C. Salt substitutes
- D. Tomatoes
Correct answer: C
Rationale: Patients taking ACE inhibitors should avoid salt substitutes as they often contain potassium, which can lead to hyperkalemia. Hyperkalemia is an elevated level of potassium in the blood that can be dangerous, especially for patients on ACE inhibitors. Vinegar, apples, and tomatoes do not pose a risk for patients taking ACE inhibitors. Therefore, the nurse should advise the patient to avoid salt substitutes to prevent potential complications.
3. A client has a new prescription for Furosemide. Which of the following adverse effects should the nurse monitor?
- A. Hyperkalemia
- B. Hyponatremia
- C. Hypernatremia
- D. Hypercalcemia
Correct answer: B
Rationale: The correct answer is B: Hyponatremia. Furosemide, a diuretic, commonly causes hyponatremia (low sodium levels) as it increases the excretion of sodium. The nurse needs to monitor the client for signs of hyponatremia, such as confusion, weakness, and muscle cramps, by checking electrolyte levels regularly. Choices A, C, and D are incorrect because hyperkalemia (choice A), hypernatremia (choice C), and hypercalcemia (choice D) are not typically associated with Furosemide use.
4. When administering IV Acyclovir to a client with Varicella, what action should the nurse take?
- A. Administer a stool softener
- B. Decrease fluid intake following infusion
- C. Infuse Acyclovir over 1 hr
- D. Monitor for hypotension
Correct answer: C
Rationale: When administering IV Acyclovir to a client with Varicella, the nurse should infuse the medication over at least 1 hour to prevent nephrotoxicity. Rapid infusion can lead to adverse effects such as renal damage. Therefore, it is crucial to follow the recommended infusion rate to ensure the client's safety and well-being. Choice A is incorrect as stool softeners are not indicated in this situation. Choice B is incorrect because fluid intake should be maintained or increased to prevent dehydration and support kidney function. Choice D is incorrect as monitoring for hypotension is not specifically related to the administration of IV Acyclovir in Varicella.
5. A patient is prescribed warfarin therapy for an artificial heart valve. Which of the following laboratory values should the nurse monitor for a therapeutic effect of warfarin?
- A. Hemoglobin
- B. Prothrombin time (PT)
- C. Bleeding time
- D. Activated partial thromboplastin time (aPTT)
Correct answer: B
Rationale: The correct answer is to monitor Prothrombin time (PT) when a patient is on warfarin therapy. Warfarin affects blood clotting, and PT is used to assess the therapeutic effect of this medication. Hemoglobin (Choice A) is not directly affected by warfarin therapy and does not reflect its therapeutic effect. Bleeding time (Choice C) measures the time it takes for bleeding to stop after a standardized cut and is not specific to warfarin therapy. Activated partial thromboplastin time (aPTT) (Choice D) is more commonly used to monitor heparin therapy, not warfarin.
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