ATI RN
ATI Pharmacology
1. A client is receiving daily doses of Oprelvekin. Which of the following laboratory values should be monitored to determine the effectiveness of this medication?
- A. Hemoglobin
- B. Absolute neutrophil count
- C. Platelet count
- D. Total white blood cell count
Correct answer: C
Rationale: Oprelvekin is a medication that stimulates platelet production. Therefore, monitoring the platelet count is essential to assess the effectiveness of this drug. The expected outcome for oprelvekin therapy is a platelet count greater than 50,000/mm^3. Changes in platelet count can indicate the response to the medication and help in adjusting the treatment plan accordingly. Monitoring hemoglobin, absolute neutrophil count, or total white blood cell count is not directly related to the mechanism of action of Oprelvekin and therefore would not provide accurate information on the drug's effectiveness.
2. What is the therapeutic classification of Furosemide?
- A. Antidiuretics
- B. Diuretics
- C. Anticonvulsants
- D. Antidotes
Correct answer: B
Rationale: Furosemide is classified therapeutically as a diuretic. Diuretics are medications used to promote diuresis, which helps the body get rid of excess salt and water. Furosemide is commonly prescribed to treat conditions such as fluid retention and swelling (edema) associated with congestive heart failure, liver disease, or kidney disorders. Choice A, Antidiuretics, is incorrect as Furosemide acts as a diuretic, promoting the production of urine. Choice C, Anticonvulsants, is also incorrect as Furosemide is not used to treat seizures. Choice D, Antidotes, is incorrect as Furosemide is not an antidote but rather a medication used to treat conditions related to fluid retention.
3. A client with peptic ulcer disease is prescribed sucralfate. Which of the following instructions should the nurse include?
- A. Take sucralfate with meals.
- B. Take sucralfate 1 hr before meals.
- C. Take sucralfate with antacids.
- D. Take sucralfate 2 hours after meals.
Correct answer: B
Rationale: The correct instruction for taking sucralfate is 1 hour before meals. This timing allows sucralfate to effectively coat the stomach lining and provide a protective barrier against gastric acid, helping to prevent ulcers.
4. A healthcare professional is preparing to administer dextrose 5% in water (D5W) 750 mL IV to infuse over 6 hr. How many mL/hr should the IV pump be set to deliver?
- A. 125 mL/hr
- B. 100 mL/hr
- C. 150 mL/hr
- D. 200 mL/hr
Correct answer: A
Rationale: To calculate the flow rate, divide the total volume by the total time: 750 mL / 6 hr = 125 mL/hr. Therefore, the IV pump should be set to deliver 125 mL/hr to infuse D5W 750 mL over 6 hours. Choice B (100 mL/hr) is incorrect because it does not accurately divide the total volume by the total time. Choice C (150 mL/hr) and Choice D (200 mL/hr) are incorrect as they are not the correct flow rates needed to infuse the D5W solution over the specified time period.
5. A client is receiving treatment with carboplatin. Which of the following findings should the nurse monitor?
- A. Hyperglycemia
- B. Ototoxicity
- C. Hypertension
- D. Bradycardia
Correct answer: B
Rationale: Corrected Rationale: Carboplatin is known to cause ototoxicity as a serious adverse effect. It is essential for the nurse to monitor the client for any signs or symptoms of hearing loss or other auditory issues to address them promptly. Incorrect Choices Rationale: A) Hyperglycemia is not a common side effect associated with carboplatin. C) Hypertension is not a typical finding to monitor for specifically related to carboplatin treatment. D) Bradycardia is not a primary concern when monitoring a client on carboplatin.
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