Nursing Elites

1. During transfusion of a unit of whole blood, a nurse is assessing a client who develops a cough, shortness of breath, elevated blood pressure, and distended neck veins. The nurse should anticipate a prescription for which of the following medications?

• A. Epinephrine
• B. Lorazepam
• C. Furosemide
• D. Diphenhydramine

Correct answer: C

Rationale: The client's symptoms indicate circulatory overload, which can occur during blood transfusions. Furosemide, a loop diuretic, is commonly prescribed in such cases to help relieve manifestations of circulatory overload by promoting diuresis and reducing fluid volume. Epinephrine is used for severe allergic reactions, lorazepam for anxiety or seizures, and diphenhydramine for mild allergic reactions or as a sedative. Therefore, the correct choice is Furosemide (C) to manage circulatory overload during a blood transfusion.

2. A client is prescribed Ciprofloxacin and seeks guidance from a nurse. Which instruction should the nurse provide?

• A. Take this medication with meals.
• B. Avoid taking this medication with dairy products.
• C. Take this medication at bedtime.
• D. Increase your intake of potassium-rich foods.

Correct answer: B

Rationale: The correct answer is B: 'Avoid taking this medication with dairy products.' Ciprofloxacin should not be taken with dairy products due to the interference of calcium with medication absorption. Taking Ciprofloxacin 1 hour before or 2 hours after consuming dairy products ensures optimal effectiveness. Choice A is incorrect because Ciprofloxacin is usually taken on an empty stomach or with a light meal, not necessarily with heavy meals. Choice C is incorrect as there is no specific instruction to take Ciprofloxacin at bedtime. Choice D is incorrect because there is no need to increase potassium-rich foods intake specifically related to Ciprofloxacin use.

3. When teaching a client with a new prescription for Timolol how to insert eye drops, which instruction should the nurse include?

• A. Press your finger on the inside corner of your eye for 1 minute after application.
• B. Apply the eye drops directly on the cornea.
• C. Drop the prescribed amount of medication into the center of the conjunctival sac.
• D. Wipe your eyes gently with a tissue immediately after application.

Correct answer: C

Rationale: The correct way to administer eye drops is by instructing the client to drop the prescribed amount of medication into the center of the conjunctival sac. This technique helps in proper distribution and absorption of the medication. Choice A is incorrect as pressing the inside corner of the eye is not necessary. Choice B is incorrect because applying eye drops directly on the cornea can cause irritation and discomfort. Choice D is incorrect as wiping the eyes immediately after application can remove the medication and reduce its effectiveness.

4. What is the appropriate medication to administer for a suspected opioid overdose in a patient who comes to the hospital?

• A. Exenatide
• B. Naloxone
• C. Heparin
• D. Tolvaptan

Correct answer: B

Rationale: The correct answer is B: Naloxone. Naloxone is the drug of choice for managing opioid overdoses as it competitively antagonizes opioid receptors, reversing the respiratory depression and sedation caused by opioids. It is crucial in the emergency treatment of opioid overdose to prevent fatal outcomes. Choices A, C, and D are incorrect. Exenatide is a medication used to treat diabetes, heparin is an anticoagulant, and tolvaptan is a diuretic. None of these medications are indicated for the management of opioid overdose.

5. Which drug undergoes extensive first-pass hepatic metabolism?

• A. Heparin
• B. Insulin
• C. Propranolol
• D. Nitroglycerin

Correct answer: C

Rationale: Propranolol undergoes extensive first-pass hepatic metabolism in the liver. When administered orally, propranolol is extensively metabolized by the liver before reaching systemic circulation, leading to reduced bioavailability. This process is known as first-pass hepatic metabolism, which significantly affects the drug's effectiveness and necessitates higher oral doses compared to other routes of administration. Heparin (Choice A) is not metabolized by the liver but excreted unchanged by the kidneys. Insulin (Choice B) is a peptide hormone that is not subject to significant first-pass metabolism. Nitroglycerin (Choice D) is primarily metabolized in the blood and tissues, bypassing significant first-pass metabolism in the liver.

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