ATI RN
Pathophysiology Practice Questions
1. A group of nursing students at Nurseslabs University is currently learning about family violence. Which of the following is true about the topic mentioned?
- A. Family violence affects every socioeconomic level.
- B. Family violence is caused by drugs and alcohol abuse.
- C. Family violence predominantly occurs in lower socioeconomic levels.
- D. Family violence rarely occurs during pregnancy.
Correct answer: A
Rationale: The correct answer is A: Family violence affects individuals across all socioeconomic levels. Family violence is not limited to any specific socioeconomic level; it can happen in any family, regardless of their economic status. Choice B is incorrect because while substance abuse can contribute to family violence, it is not the sole cause. Choice C is incorrect as family violence can occur in families from all socioeconomic backgrounds. Choice D is incorrect as family violence can indeed occur during pregnancy, posing serious risks to both the mother and the unborn child.
2. Multiple sclerosis manifests as asymmetrical and in different parts of the body because:
- A. Autoreactive lymphocytes are causing diffuse patchy damage to the myelin sheath in the central nervous system.
- B. Acetylcholine receptors are destroyed by immunoglobulin G.
- C. Autoreactive T lymphocytes cause progressive loss of neurons in the substantia nigra.
- D. Cortical motor cells degenerate.
Correct answer: A
Rationale: The correct answer is A. Multiple sclerosis is characterized by the immune system attacking the myelin sheath in the central nervous system. This attack leads to patchy damage on the myelin sheath, resulting in asymmetrical neurological symptoms. Choices B, C, and D are incorrect because they do not accurately describe the pathophysiology of multiple sclerosis. In multiple sclerosis, it is the autoreactive lymphocytes that target and damage the myelin sheath, not acetylcholine receptors, T lymphocytes, or cortical motor cells.
3. What are direct effects of antibodies? (Select ONE that does not apply):
- A. Neutralization
- B. Agglutination
- C. Precipitation
- D. Phagocytosis
Correct answer: D
Rationale: The direct effects of antibodies include neutralization, agglutination, and precipitation. Antibodies neutralize pathogens by binding to them and preventing their harmful effects. Agglutination involves the clumping together of pathogens, making it easier for phagocytes to engulf them. Precipitation refers to the process where antibodies bind to soluble antigens, forming large complexes that are easily removed from the body. Phagocytosis, on the other hand, is an indirect effect of antibodies where phagocytes engulf and destroy pathogens opsonized by antibodies, not a direct effect.
4. What is a common factor related to all forms of heart failure?
- A. Peripheral edema
- B. Pulmonary edema
- C. Reduced cardiac output
- D. Jugular vein distention
Correct answer: C
Rationale: The correct answer is C: Reduced cardiac output. All forms of heart failure share this common factor, which occurs when the heart is unable to pump enough blood to meet the body's needs. Choices A, B, and D are incorrect. While peripheral edema and pulmonary edema can be symptoms of heart failure, they are not universal to all forms. Jugular vein distention is a sign of right heart failure, not a common factor across all types of heart failure.
5. Which immunoglobulin presents the first challenge to the antigen?
- A. IgA
- B. IgG
- C. IgM
- D. IgE
Correct answer: C
Rationale: IgM is the first immunoglobulin to challenge the antigen during an immune response. IgM is the primary antibody produced during the initial or primary immune response. It is efficient in agglutination and complement activation, making it crucial in the early stages of defense. IgA is mainly found in mucosal areas and secretions. IgG is the most abundant antibody in circulation and is involved in secondary immune responses. IgE is primarily associated with allergic reactions and parasitic infections. Therefore, IgM is the correct choice as it acts first during the immune response, while the other immunoglobulins have different roles and functions.
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