ATI RN
ATI Pharmacology
1. An adolescent client has a new prescription for Clomipramine for OCD. Which of the following instructions should the nurse include to minimize an adverse effect of this medication?
- A. Wear sunglasses when outdoors.
- B. Check your temperature daily.
- C. Take this medication in the morning.
- D. Add extra calories to your diet.
Correct answer: A
Rationale: To minimize the adverse effect of photophobia associated with Clomipramine, the client should be advised to wear sunglasses when outdoors. Clomipramine is a tricyclic antidepressant (TCA) known to cause anticholinergic effects like photophobia, which can be reduced by protecting the eyes with sunglasses when exposed to bright light. Choices B, C, and D are incorrect because checking temperature daily, taking the medication in the morning, and adding extra calories to the diet are not specifically related to minimizing the adverse effect of photophobia caused by Clomipramine.
2. Which of the following is not related to drug toxicity of Atenolol?
- A. CHF
- B. Tachycardia
- C. AV block
- D. Sedative appearance
Correct answer: B
Rationale: Atenolol, a beta-blocker, is not typically associated with tachycardia. Instead, drug toxicity of Atenolol is more commonly linked to bradycardia due to its beta-blocking effects on the heart's electrical conduction system. Symptoms of Atenolol toxicity may include heart failure (CHF), AV block, and a sedative appearance, but not tachycardia.
3. A healthcare professional is preparing to administer Butorphanol to a client who has a history of substance use disorder. The healthcare professional should identify which of the following information as true regarding Butorphanol?
- A. Butorphanol has a lower risk of abuse than morphine.
- B. Butorphanol causes a lower incidence of respiratory depression than morphine.
- C. Butorphanol can be reversed with an opioid antagonist.
- D. Butorphanol can cause abstinence syndrome in opioid-dependent clients.
Correct answer: D
Rationale: The correct answer is D. Butorphanol is an opioid agonist/antagonist that can precipitate withdrawal symptoms in opioid-dependent individuals. Symptoms of abstinence syndrome can include abdominal pain, fever, and anxiety. This occurs because butorphanol competes with and displaces opioid agonists from receptors, leading to withdrawal symptoms in opioid-dependent clients. Choices A, B, and C are incorrect. Butorphanol does not have a lower risk of abuse than morphine, it can cause respiratory depression similar to other opioids, and although it is an opioid antagonist, it does not get reversed by opioid antagonists.
4. A client has a new prescription for Nevirapine, an NNRTI. Which of the following statements should the nurse include in discharge teaching?
- A. Take this medication with food to increase absorption.
- B. Avoid alcohol while taking this medication.
- C. Take this medication at the same time every day.
- D. Take this medication on an empty stomach.
Correct answer: B
Rationale: The correct statement to include in discharge teaching about Nevirapine, an NNRTI, is to advise the client to avoid alcohol while taking this medication. Alcohol can interact with Nevirapine and lead to potential adverse effects or decreased effectiveness. Choice A is incorrect because Nevirapine should be taken without food or on an empty stomach for optimal absorption. Choice C is a general recommendation for most medications but not specifically for Nevirapine. Choice D is incorrect as Nevirapine should not be taken on an empty stomach.
5. A healthcare provider is planning care for a client with brain cancer experiencing headaches. Which of the following adjuvant medications is indicated for this client?
- A. Dexamethasone
- B. Methylphenidate
- C. Hydroxyzine
- D. Amitriptyline
Correct answer: A
Rationale: Dexamethasone, a glucocorticoid, is indicated for clients with brain cancer experiencing headaches as it decreases inflammation and swelling. It is commonly used to reduce cerebral edema and relieve pressure caused by the tumor. Methylphenidate (Choice B) is a central nervous system stimulant used in conditions like ADHD and narcolepsy, not for brain cancer headaches. Hydroxyzine (Choice C) is an antihistamine used for anxiety and allergic conditions, not indicated for brain cancer headaches. Amitriptyline (Choice D) is a tricyclic antidepressant used for depression, neuropathic pain, and migraine prophylaxis, but not typically indicated for brain cancer headaches.
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