ATI RN
ATI Pharmacology Test Bank
1. When starting a new prescription for prednisone, which instruction should the nurse include for the client?
- A. Increase your intake of potassium-rich foods.
- B. Do not stop taking this medication abruptly.
- C. Avoid grapefruit juice while taking this medication.
- D. Take the medication at bedtime to prevent drowsiness.
Correct answer: B
Rationale: The correct instruction for a client starting a new prescription for prednisone is not to stop taking the medication abruptly. Abrupt discontinuation of prednisone can lead to adrenal insufficiency, emphasizing the importance of gradual tapering under healthcare provider guidance. Increasing potassium-rich foods may be necessary based on individual needs, but it is not the priority instruction in this context. Grapefruit juice interaction is more commonly associated with certain medications but not specifically with prednisone. Taking prednisone at bedtime to prevent drowsiness is not a key instruction related to its administration.
2. A client has a new diagnosis of Fibromyalgia. Which of the following medications should the nurse anticipate being prescribed for this client?
- A. Colchicine
- B. Hydroxychloroquine
- C. Auranofin
- D. Duloxetine
Correct answer: D
Rationale: The correct answer is Duloxetine. Duloxetine is commonly used to treat fibromyalgia as a serotonin-norepinephrine reuptake inhibitor. It is also indicated for depression and diabetic peripheral neuropathy. Colchicine, Hydroxychloroquine, and Auranofin are not typically prescribed for fibromyalgia. Colchicine is primarily used to treat gout, Hydroxychloroquine for conditions like malaria and rheumatoid arthritis, and Auranofin for rheumatoid arthritis.
3. A client has a prescription for Desmopressin for the treatment of Diabetes Insipidus. Which of the following instructions should the nurse include in the teaching?
- A. Decrease fluid intake at the start of treatment.
- B. Monitor for nocturia.
- C. Report a weight loss of 0.5 kg (1.1 lb) per week.
- D. Expect permanent polyuria with this medication.
Correct answer: A
Rationale: Desmopressin is a medication used to reduce diuresis in clients with diabetes insipidus. To prevent water intoxication, clients should be advised to decrease fluid intake at the beginning of treatment. This instruction helps to balance fluid levels in the body and prevent potential complications associated with excessive fluid intake while on Desmopressin therapy. Monitoring for signs of fluid retention, such as weight gain, and adjusting fluid intake accordingly are essential components of client education when initiating treatment with Desmopressin.
4. A healthcare provider is providing discharge instructions to a client who is prescribed Enalapril. Which of the following adverse effects should the healthcare provider instruct the client to monitor?
- A. Dry cough
- B. Weight gain
- C. Diarrhea
- D. Nausea
Correct answer: A
Rationale: The correct answer is A: Dry cough. A persistent dry cough is a common adverse effect of Enalapril, an ACE inhibitor. Enalapril can cause a non-productive cough due to its effect on bradykinin levels. The client should be advised to report this symptom to their healthcare provider to consider alternative treatments. Choices B, C, and D are incorrect because weight gain, diarrhea, and nausea are not typically associated with Enalapril use.
5. A client is receiving daily doses of Oprelvekin. Which of the following laboratory values should be monitored to determine the effectiveness of this medication?
- A. Hemoglobin
- B. Absolute neutrophil count
- C. Platelet count
- D. Total white blood cell count
Correct answer: C
Rationale: Oprelvekin is a medication that stimulates platelet production. Therefore, monitoring the platelet count is essential to assess the effectiveness of this drug. The expected outcome for oprelvekin therapy is a platelet count greater than 50,000/mm^3. Changes in platelet count can indicate the response to the medication and help in adjusting the treatment plan accordingly. Monitoring hemoglobin, absolute neutrophil count, or total white blood cell count is not directly related to the mechanism of action of Oprelvekin and therefore would not provide accurate information on the drug's effectiveness.
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