ATI RN
ATI Pharmacology Proctored Exam 2023
1. A client has a new prescription for Warfarin. Which of the following herbal supplements should the client be instructed to avoid?
- A. St. John's wort
- B. Echinacea
- C. Garlic
- D. Ginseng
Correct answer: A
Rationale: St. John's wort should be avoided by clients taking Warfarin as it can reduce the medication's effectiveness by affecting its metabolism. Echinacea, garlic, and ginseng are also known to interact with Warfarin, either by increasing the risk of bleeding or altering its anticoagulant effects. However, St. John's wort is particularly significant due to its potent enzyme-inducing properties that can lead to subtherapeutic levels of Warfarin, potentially increasing the risk of blood clots.
2. What is the antidote for Heparin?
- A. Protamine sulfate
- B. Narcan
- C. Romazicon
- D. Naloxone
Correct answer: A
Rationale: The correct answer is A: Protamine sulfate. Heparin is an anticoagulant medication used to prevent blood clots. In cases of overdose or excessive bleeding due to Heparin, protamine sulfate is administered as the specific antidote. Protamine sulfate works by neutralizing Heparin's anticoagulant activity. Choices B, C, and D are incorrect. Narcan (Naloxone) is used to reverse opioid overdose, Romazicon (Flumazenil) is used to reverse benzodiazepine overdose, and Naloxone is also used to reverse opioid overdose but is not the antidote for Heparin.
3. A client has been on levothyroxine therapy for several months. Which of the following findings indicates a therapeutic response to the medication?
- A. Decrease in level of thyroxine (T4)
- B. Increase in weight
- C. Increase in hours of sleep per night
- D. Decrease in level of thyroid stimulating hormone (TSH)
Correct answer: D
Rationale: A therapeutic response to levothyroxine is indicated by a decrease in the level of TSH. This decrease signifies that the body requires less stimulation to produce thyroid hormone, reflecting a normalization of thyroid function due to the medication's effectiveness. Choices A, B, and C are incorrect as an increase in T4 levels, weight gain, and increased sleep hours are not indicative of a therapeutic response to levothyroxine therapy.
4. A client with heart failure is prescribed digoxin. Which statement by the client indicates an adverse effect of the medication?
- A. I can walk a mile a day.
- B. I've had a backache for several days.
- C. I am urinating more frequently.
- D. I feel nauseated and have no appetite.
Correct answer: D
Rationale: Nausea and loss of appetite are common early signs of digoxin toxicity, indicating an adverse effect of the medication. These symptoms should be reported to the healthcare provider immediately for further evaluation and management.
5. A client is starting therapy with cisplatin. The healthcare provider should instruct the client to report which of the following adverse effects?
- A. Tinnitus
- B. Nausea
- C. Constipation
- D. Weight gain
Correct answer: A
Rationale: The correct answer is tinnitus. Cisplatin can cause ototoxicity, which may manifest as tinnitus. Tinnitus should be reported promptly to the healthcare provider to prevent further hearing damage.
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