ATI RN
ATI Pharmacology Proctored Exam 2024
1. What is the pharmacological action of metformin?
- A. Blocks stimulation of beta1 and beta2.
- B. Blocks vasoconstriction and aldosterone.
- C. Acts at many levels in the CNS to produce an anxiolytic effect.
- D. Decreases hepatic glucose production.
Correct answer: D
Rationale: The correct answer is D: Decreases hepatic glucose production. Metformin's primary pharmacological action is to decrease hepatic glucose production, leading to lower blood sugar levels and improved insulin sensitivity in the liver. Choices A, B, and C are incorrect because metformin does not block stimulation of beta1 and beta2 receptors, vasoconstriction, aldosterone, or act in the CNS to produce an anxiolytic effect. Therefore, these options are not reflective of metformin's mechanism of action.
2. A client has a new prescription for Amlodipine. Which of the following instructions should the nurse include during discharge teaching?
- A. Take the medication at bedtime.
- B. Avoid drinking grapefruit juice.
- C. Increase your intake of high-sodium foods.
- D. Expect a dry cough.
Correct answer: B
Rationale: The correct instruction for the nurse to include during discharge teaching is to advise the client to avoid drinking grapefruit juice. Grapefruit juice can inhibit the metabolism of amlodipine, a calcium channel blocker, leading to increased drug levels in the blood. This can result in potentiated side effects and potential toxicity. Option A is incorrect as amlodipine is usually taken once daily, not specifically at bedtime. Option C is incorrect because high-sodium foods are generally discouraged in individuals with hypertension. Option D is incorrect as a dry cough is not an expected side effect of amlodipine.
3. A client has a new prescription for Allopurinol. Which of the following instructions should the nurse include?
- A. Take this medication at bedtime.
- B. Increase your fluid intake.
- C. Avoid foods high in calcium.
- D. Take this medication with meals.
Correct answer: B
Rationale: Allopurinol can cause kidney stones due to the formation of uric acid crystals, so it is crucial for the client to increase their fluid intake. Adequate hydration helps to prevent the formation of kidney stones by diluting the urine and promoting the excretion of uric acid. Therefore, advising the client to increase their fluid intake is essential in preventing this adverse effect while taking Allopurinol.
4. A client with heart failure is prescribed digoxin. Which statement by the client indicates an adverse effect of the medication?
- A. I can walk a mile a day.
- B. I've had a backache for several days.
- C. I am urinating more frequently.
- D. I feel nauseated and have no appetite.
Correct answer: D
Rationale: Nausea and loss of appetite are common early signs of digoxin toxicity, indicating an adverse effect of the medication. These symptoms should be reported to the healthcare provider immediately for further evaluation and management.
5. A client has a new prescription for Metoprolol to treat hypertension. Which of the following instructions should the nurse include?
- A. Stop taking the medication if your heart rate is below 70/min.
- B. Take the medication with food.
- C. Avoid sudden changes in position.
- D. Limit your sodium intake while taking this medication.
Correct answer: C
Rationale: The correct instruction for a client taking Metoprolol, a medication used to treat hypertension, is to avoid sudden changes in position. Metoprolol can cause orthostatic hypotension, a sudden drop in blood pressure when moving from lying down to standing up, leading to dizziness and falls. By advising the client to change positions slowly, the nurse helps prevent these adverse effects and promotes safety.
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