ATI RN
ATI Pharmacology Proctored Exam 2023
1. A healthcare professional is preparing to administer heparin 15,000 units subcutaneously every 12 hours. The available heparin injection is 20,000 units/mL. How many milliliters should the healthcare professional administer per dose?
- A. 0.8 mL
- B. 0.75 mL
- C. 0.5 mL
- D. 1 mL
Correct answer: A
Rationale: To calculate the volume to administer, use the formula: Desired dose / Concentration = Volume to administer. In this case, (15,000 units / 20,000 units/mL) = 0.75 mL. Since the volume needs to be rounded up to the nearest tenth, the correct answer is 0.8 mL. Choice B (0.75 mL) is incorrect because it does not account for rounding up the volume. Choices C (0.5 mL) and D (1 mL) are incorrect as they do not reflect the precise calculation based on the given concentration and desired dose.
2. A client is taking Propylthiouracil. For which of the following adverse effects of this medication should the nurse monitor?
- A. Bradycardia
- B. Insomnia
- C. Heat intolerance
- D. Weight loss
Correct answer: A
Rationale: Propylthiouracil is a medication used to treat hyperthyroidism. One of the adverse effects of Propylthiouracil is bradycardia, which is a slower than normal heart rate. Since the medication works by decreasing thyroid hormone production, it can lead to hypothyroidism as a side effect, causing bradycardia. Therefore, the nurse should monitor the client for signs and symptoms of bradycardia while taking Propylthiouracil. Choices B, C, and D are incorrect because insomnia, heat intolerance, and weight loss are not typically associated adverse effects of Propylthiouracil.
3. A client has a new prescription for a Nitroglycerin transdermal patch for Angina Pectoris. Which of the following instructions should the nurse include?
- A. Remove the patch each evening.
- B. Do not cut the patch in half even if angina attacks are under control.
- C. Remove the nitroglycerin patch for 30 minutes if a headache occurs.
- D. Apply a new patch every 48 hours.
Correct answer: A
Rationale: The correct instruction for a client using a Nitroglycerin transdermal patch is to remove the patch each evening to prevent tolerance. This allows for a nitrate-free period of 10 to 12 hours during each 24-hour period, reducing the risk of developing tolerance to the medication. Choice B is incorrect because cutting the patch could alter the dose delivery and is not recommended. Choice C is incorrect as removing the patch for 30 minutes when a headache occurs may not be effective in managing symptoms. Choice D is incorrect as Nitroglycerin patches are usually applied once daily, not every 48 hours.
4. A client has a Cerebrospinal fluid infection with gram-negative bacteria. Which of the following Cephalosporin antibiotics should be administered IV to treat this infection?
- A. Cefaclor
- B. Cefazolin
- C. Cefepime
- D. Cephalexin
Correct answer: C
Rationale: In treating a Cerebrospinal fluid infection caused by gram-negative bacteria, Cefepime, a fourth-generation cephalosporin, is the most suitable choice due to its enhanced efficacy against gram-negative organisms in such infections. Cefaclor (Choice A) is a second-generation cephalosporin more commonly used for respiratory tract infections. Cefazolin (Choice B) is a first-generation cephalosporin often used for skin and soft tissue infections. Cephalexin (Choice D) is a first-generation cephalosporin indicated for skin and urinary tract infections, but not the optimal choice for a Cerebrospinal fluid infection with gram-negative bacteria.
5. When teaching a client with a prescription for Phenytoin, which of the following instructions should the nurse include?
- A. Expect the development of a mild rash.
- B. Take the medication on an empty stomach.
- C. Monitor for signs of gingival hyperplasia.
- D. Increase your intake of calcium.
Correct answer: C
Rationale: Phenytoin is known to cause gingival hyperplasia, a condition characterized by overgrowth of gum tissue. The nurse should instruct the client to monitor for signs of gingival hyperplasia, such as swollen or bleeding gums. Good oral hygiene practices are essential to prevent or manage this side effect. Choices A, B, and D are incorrect. Phenytoin does not typically cause a mild rash, should be taken with food to reduce gastrointestinal upset, and does not warrant an increase in calcium intake.
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