ATI RN
ATI Proctored Pharmacology Test
1. A client asks the nurse how Rituximab works, which the client is receiving to treat Non-Hodgkin's Leukemia. Which of the following should the nurse include?
- A. Blocks hormone receptors
- B. Increases immune response
- C. Binds with specific antigens on tumor cells
- D. Stops DNA replication during cell division
Correct answer: C
Rationale: Rituximab is a monoclonal antibody that binds with specific antigens on B-lymphocytes, leading to the destruction of cancer cells. In the context of Non-Hodgkin's Leukemia, Rituximab targets and destroys cancerous B-lymphocytes, which helps in treating the disease. Choices A, B, and D are incorrect. Rituximab does not block hormone receptors, increase immune response, or stop DNA replication during cell division. The primary mode of action of Rituximab is its binding with specific antigens on tumor cells, specifically B-lymphocytes, to elicit an immune response against cancerous cells.
2. A client with Schizophrenia is taking Risperidone. Which of the following instructions should the nurse include in the teaching?
- A. Increase your intake of snacks to prevent weight loss.
- B. Notify the provider if you develop breast enlargement.
- C. Be aware of the possibility of mild seizures while taking this medication.
- D. Expect an increase in libido when taking this medication.
Correct answer: B
Rationale: The correct instruction the nurse should provide to the client taking Risperidone for Schizophrenia is to notify the provider if they develop breast enlargement. Risperidone can lead to an increase in prolactin levels, causing gynecomastia (breast enlargement) and galactorrhea. Therefore, it is crucial for the client to report these manifestations to the healthcare provider for appropriate management. Choices A, C, and D are incorrect. Increasing snack intake to prevent weight loss is not a specific concern related to Risperidone. Mild seizures are not a common side effect of Risperidone, so this instruction is unnecessary. Risperidone is more likely to cause sexual side effects like decreased libido rather than an increase.
3. A client is receiving imatinib. Which of the following adverse effects should the nurse monitor?
- A. Edema
- B. Constipation
- C. Dry mouth
- D. Urinary retention
Correct answer: A
Rationale: The correct answer is A: Edema. The nurse should monitor the client for edema when receiving imatinib. Imatinib, a tyrosine kinase inhibitor, can lead to fluid retention and edema as a common adverse effect. This can manifest as swelling in various parts of the body, indicating the need for close monitoring by the nurse to prevent complications related to fluid overload. Choices B, C, and D are incorrect because constipation, dry mouth, and urinary retention are not typically associated with imatinib use. Therefore, they are not the priority adverse effects to monitor in a client receiving this medication.
4. A client has a new prescription for Somatropin to stimulate growth. The client should monitor for which of the following adverse effects?
- A. Hyperglycemia.
- B. Bradycardia.
- C. Urinary frequency.
- D. Edema.
Correct answer: A
Rationale: Somatropin is known to cause hyperglycemia as a common adverse effect. Therefore, the client should be instructed to monitor for elevated blood glucose levels closely while taking this medication to ensure early detection and management of hyperglycemia.
5. A client has a new prescription for Warfarin. Which of the following herbal supplements should the client be instructed to avoid?
- A. St. John's wort
- B. Echinacea
- C. Garlic
- D. Ginseng
Correct answer: A
Rationale: St. John's wort should be avoided by clients taking Warfarin as it can reduce the medication's effectiveness by affecting its metabolism. Echinacea, garlic, and ginseng are also known to interact with Warfarin, either by increasing the risk of bleeding or altering its anticoagulant effects. However, St. John's wort is particularly significant due to its potent enzyme-inducing properties that can lead to subtherapeutic levels of Warfarin, potentially increasing the risk of blood clots.
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