ATI RN
ATI Pharmacology
1. A client has a prescription for Bethanechol to treat urinary retention. Which of the following findings is a manifestation of muscarinic stimulation?
- A. Dry mouth
- B. Hypertension
- C. Excessive perspiration
- D. Fecal impaction
Correct answer: C
Rationale: The correct answer is C: Excessive perspiration. Bethanechol is a muscarinic agonist that stimulates muscarinic receptors. Activation of muscarinic receptors can lead to excessive perspiration (diaphoresis) due to increased cholinergic activity, affecting sweat glands. Dry mouth, hypertension, and fecal impaction are not typically associated with muscarinic stimulation. Dry mouth is more commonly associated with anticholinergic medications, hypertension can be a result of alpha-adrenergic stimulation, and fecal impaction is not a direct effect of muscarinic receptor activation.
2. A nurse is providing instructions to a client who has a prescription for Amoxicillin and Clarithromycin to treat a Peptic Ulcer. Which of the following information should the nurse include in the teaching?
- A. Take these medications with foo '
- B. These medications can turn your stool black.'
- C. These medications can cause photosensitivity.'
- D. The purpose of these medications is to decrease the pH of gastric juices in the stomach.'
Correct answer: A
Rationale: The nurse should instruct the client to take these medications with food to reduce GI disturbances.
3. What is the action of Metformin?
- A. Decreasing intestinal glucose absorption
- B. Increasing sensitivity to insulin
- C. Decreasing hepatic glucose production
- D. All of the above
Correct answer: D
Rationale: Metformin exerts its effects by decreasing hepatic glucose production, increasing sensitivity to insulin, and decreasing intestinal glucose absorption. These actions help in lowering blood glucose levels and improving insulin sensitivity in individuals with diabetes.
4. A client is receiving treatment with irinotecan. Which of the following findings should the nurse monitor?
- A. Diarrhea
- B. Hypertension
- C. Ototoxicity
- D. Neutropenia
Correct answer: A
Rationale: Corrected Rationale: Irinotecan is known to commonly cause diarrhea as an adverse effect due to its impact on the gastrointestinal tract. Therefore, the nurse should closely monitor the client for signs of diarrhea while receiving this treatment. Choices B, C, and D are incorrect because irinotecan is not typically associated with hypertension, ototoxicity, or neutropenia as primary adverse effects. While these side effects can occur with other medications, they are not the main concerns when monitoring a client receiving irinotecan.
5. A healthcare professional is preparing to administer an IV antibiotic to a client who has a systemic infection. Which of the following actions should the professional take first?
- A. Administer an antihistamine prior to the antibiotic.
- B. Monitor the client's urine output.
- C. Check the client's allergy history.
- D. Assess the client's vital signs.
Correct answer: C
Rationale: The first action the healthcare professional should take is to check the client's allergy history before administering the antibiotic to prevent a potential allergic reaction. It is crucial to identify any known allergies to antibiotics to ensure the client's safety and well-being. Administering an antihistamine prior to the antibiotic (Choice A) is not recommended unless an allergic reaction occurs. Monitoring the client's urine output (Choice B) and assessing the client's vital signs (Choice D) are important but not the first step in this situation. Checking the client's allergy history takes precedence to prevent adverse reactions.
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