ATI RN
ATI Pathophysiology Final Exam
1. Which of the following mediators of inflammation causes increased capillary permeability and pain?
- A. Serotonin
- B. Histamine
- C. Bradykinin
- D. Nitric oxide
Correct answer: C
Rationale: Bradykinin is the correct answer. It is a potent mediator of inflammation that causes increased capillary permeability and is responsible for the pain associated with inflammation. Serotonin and histamine are also mediators of inflammation, but they are not primarily known for increasing capillary permeability or inducing pain. Nitric oxide is involved in various physiological processes but is not a primary mediator of inflammation that causes increased capillary permeability and pain.
2. The canola plant's genome is altered to produce an herbicide-resistant crop. The canola oil produced from this crop is an example of a:
- A. pesticide-free food.
- B. saturated fat food.
- C. genetically modified food.
- D. product that is pure.
Correct answer: C
Rationale: The correct answer is C: genetically modified food. Canola plants with altered genomes to be herbicide-resistant are an example of genetically modified organisms (GMOs). Genetically modified foods have their genetic material modified for various purposes, such as enhancing resistance to pests, herbicides, or improving nutritional content. Choice A, 'pesticide-free food,' is incorrect because genetic modification does not necessarily make the food pesticide-free. Choice B, 'saturated fat food,' is incorrect as it does not relate to the genetic modification of the canola plant. Choice D, 'product that is pure,' is too vague and does not specifically address the genetic modification aspect of the canola plant.
3. Medroxyprogesterone acetate (Provera) is indicated for the treatment of women with
- A. uterine bleeding.
- B. cervical cancer.
- C. ovarian cancer.
- D. fibromyalgia.
Correct answer: A
Rationale: Medroxyprogesterone acetate (Provera) is commonly used to treat conditions like abnormal uterine bleeding, amenorrhea, and endometriosis. It helps regulate the menstrual cycle and reduce excessive bleeding. Therefore, the correct answer is A. Choice B, cervical cancer, is incorrect because Provera is not indicated for the treatment of cancer. Choice C, ovarian cancer, is also incorrect as Provera is not a primary treatment for ovarian cancer. Choice D, fibromyalgia, is unrelated to the use of medroxyprogesterone acetate.
4. After a generalized seizure, a 27-year-old woman with epilepsy feels tired and falls asleep. This is:
- A. an ominous sign.
- B. normal and termed the postictal period.
- C. a reflection of an underlying brain tumor.
- D. only worrisome if there are focal neurologic deficits after.
Correct answer: B
Rationale: Choice B is the correct answer. The postictal period is the phase following a seizure, characterized by symptoms like fatigue, confusion, and sleepiness. It is a normal part of the seizure process and does not necessarily indicate a serious underlying issue. Choice A is incorrect because feeling tired and falling asleep after a seizure is expected and not an ominous sign. Choice C is incorrect as there is no indication in the scenario provided to suggest an underlying brain tumor. Choice D is incorrect because the presence of focal neurologic deficits would indeed be concerning, but the postictal state itself is a common and expected occurrence post-seizure.
5. A female patient has been diagnosed with tuberculosis and begun multiple-drug therapy. The woman has asked the nurse why it is necessary for her to take several different drugs instead of one single drug. How should the nurse best respond to the patient's question?
- A. “Multiple drugs are used because doctors need to combat the TB bacteria from different angles to effectively treat the infection.”
- B. “The use of multiple drugs prevents the development of drug-resistant TB.”
- C. “Multiple drugs are prescribed because the final testing results for TB can take up to 3 weeks to confirm the most effective treatment.”
- D. “Multiple drugs are used in order to speed up the course of treatment.”
Correct answer: B
Rationale: The correct answer is B. Using multiple drugs in tuberculosis treatment helps prevent the development of drug-resistant TB. This approach is crucial because if the infection is not completely eradicated, the remaining bacteria may become resistant to the single drug used, making future treatments less effective. Choice A is incorrect because the use of multiple drugs is not due to uncertainty about which drug will work, but rather to address the bacteria from different angles. Choice C is incorrect as it misleads the patient about the reason for using multiple drugs. Choice D is also incorrect because the primary purpose of using multiple drugs is not to speed up treatment but to ensure effectiveness and prevent resistance.
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