ATI RN
ATI Pharmacology Proctored
1. Which of the following is not directly related to the drug toxicity of Ibuprofen?
- A. Nausea
- B. Renal dysfunction
- C. Anemia
- D. Muscle wasting
Correct answer: D
Rationale: Ibuprofen is known to cause adverse effects such as nausea, renal dysfunction, and anemia. However, muscle wasting is not a common toxicity associated with Ibuprofen use. Therefore, the correct answer is D.
2. When taking Digoxin, low levels of what can cause toxicity?
- A. Potassium
- B. Calcium
- C. Sodium
- D. Magnesium
Correct answer: A
Rationale: Low potassium levels can lead to Digoxin toxicity. Digoxin competes with potassium for binding sites on the sodium-potassium pump. When potassium levels are low, there is an increased risk of Digoxin binding and toxicity. Choice B (Calcium) is incorrect because low calcium levels are not directly linked to Digoxin toxicity. Choice C (Sodium) is incorrect as low sodium levels do not cause Digoxin toxicity. Choice D (Magnesium) is incorrect as low magnesium levels do not contribute to Digoxin toxicity.
3. A healthcare provider is reviewing the health history of a client who is starting therapy with tamoxifen. The healthcare provider should recognize that tamoxifen is contraindicated in which of the following clients?
- A. A client with a history of deep-vein thrombosis
- B. A client with a history of migraine headaches
- C. A client with a history of hypertension
- D. A client with a history of anemia
Correct answer: A
Rationale: Tamoxifen is contraindicated in clients with a history of thromboembolic events, such as deep-vein thrombosis, due to the increased risk of blood clots forming and leading to serious complications like pulmonary embolism. Clients with a history of deep-vein thrombosis are at a higher risk of recurrent thromboembolic events when taking tamoxifen, making it unsafe for such individuals. Choices B, C, and D are not contraindications for tamoxifen therapy, as migraine headaches, hypertension, and anemia do not directly interact with tamoxifen's mechanism of action or pose significant risks when used together.
4. A healthcare provider is teaching a client who has a new prescription for Bisacodyl suppositories. Which of the following information should the provider include?
- A. Expect results within 15 to 60 minutes.
- B. Insert the suppository as directed by the healthcare provider.
- C. Keep the suppository at room temperature.
- D. Expect rectal burning.
Correct answer: D
Rationale: When educating a client about Bisacodyl suppositories, it is important to include information about the common side effects. Rectal burning is a frequent side effect that can occur after using Bisacodyl suppositories, so the client should be informed to expect this discomfort. The onset of action for Bisacodyl suppositories is typically within 15 to 60 minutes, so the client should expect results relatively quickly, not in 6 to 12 hours. It is essential to follow the healthcare provider's instructions on how to insert the suppository correctly. Keeping the suppository at room temperature is sufficient; refrigeration is not required. Therefore, option D is the correct choice as it addresses a common side effect and prepares the client for potential discomfort. Options A, B, and C are incorrect as they do not focus on a significant side effect, proper administration, or storage requirements.
5. A client is taking Spironolactone. Which of the following laboratory findings should the nurse monitor and report to the provider?
- A. Sodium level of 138 mEq/L
- B. Potassium level of 5.2 mEq/L
- C. Chloride level of 100 mEq/L
- D. Calcium level of 9.5 mg/dL
Correct answer: B
Rationale: The correct answer is B: Potassium level of 5.2 mEq/L. Spironolactone is a potassium-sparing diuretic that can lead to hyperkalemia (elevated potassium levels). A potassium level of 5.2 mEq/L is considered elevated and should be reported to the provider for further assessment and management to prevent potential complications. Choices A, C, and D are not directly affected by Spironolactone and do not typically require immediate reporting unless there are other underlying issues or specific instructions for those electrolytes.
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