ace inhibitors

ATI RN

ATI Proctored Pharmacology Test

1. How do ACE inhibitors work?

A. Block the vasoconstrictor and aldosterone effects of angiotensin II at the receptor site
B. Block stimulation of beta 1 and beta 2 at the receptor sites
C. Block the conversion of angiotensin I to the vasoconstrictor angiotensin II
D. None of the above

Correct answer: C

Rationale: ACE inhibitors work by inhibiting the conversion of angiotensin I to angiotensin II. Angiotensin II is a potent vasoconstrictor, and by blocking its production, ACE inhibitors help dilate blood vessels, reduce blood pressure, and decrease the workload of the heart. Choice A is incorrect because it describes the mechanism of action of angiotensin receptor blockers (ARBs), not ACE inhibitors. Choice B is incorrect as it describes beta-blockers, not ACE inhibitors. Choice D is incorrect as ACE inhibitors do have a specific mechanism of action.

2. Which medication is used as a bronchodilator?

A. Warfarin
B. Lovastatin
C. Albuterol
D. Valproate

Correct answer: C

Rationale: Albuterol is the correct answer. It is a medication commonly used as a bronchodilator to treat conditions such as asthma. Albuterol works by relaxing the muscles in the airways, allowing better airflow and making breathing easier for individuals with respiratory conditions. Warfarin (Choice A) is an anticoagulant used to prevent blood clots, Lovastatin (Choice B) is a medication used to lower cholesterol levels, and Valproate (Choice D) is used to treat seizures and bipolar disorder. These medications are not bronchodilators and are used for different medical conditions.

3. A client receives a local anesthetic of Lidocaine during the repair of a skin laceration. For which of the following adverse reactions should the nurse monitor the client?

A. Seizures
B. Tachycardia
C. Hypertension
D. Fever

Correct answer: A

Rationale: Seizures are a potential adverse reaction to local anesthetics like Lidocaine. Lidocaine can affect the central nervous system and, in some cases, lead to seizure activity. Therefore, it is important for the nurse to monitor the client for any signs of seizures during and after the administration of Lidocaine.

4. A client has a new prescription for Phenytoin. Which of the following instructions should the nurse include?

A. Brush and floss your teeth regularly.
B. Avoid drinking grapefruit juice.
C. Take this medication with food.
D. Increase your intake of calcium-rich foods.

Correct answer: A

Rationale: The correct answer is to instruct the client to brush and floss their teeth regularly. Phenytoin can lead to gingival hyperplasia, making oral hygiene crucial to prevent complications. Encouraging good oral care practices helps reduce the risk of adverse effects on the gums and teeth. Avoiding grapefruit juice is not specifically related to Phenytoin. While some medications require intake with food, Phenytoin is usually taken on an empty stomach for better absorption. Increasing calcium-rich foods is not directly associated with Phenytoin therapy.

5. A healthcare professional is preparing to administer verapamil by IV bolus to a client who is experiencing cardiac dysrhythmias. For which of the following adverse effects should the healthcare professional monitor when giving this medication?

A. Hyperthermia
B. Hypotension
C. Ototoxicity
D. Muscle pain

Correct answer: B

Rationale: Verapamil is known to cause hypotension as one of its adverse effects due to its vasodilatory properties. Therefore, it is essential for the healthcare professional to monitor the client's blood pressure closely during and after administration to prevent complications such as severe hypotension. Hyperthermia, ototoxicity, and muscle pain are not commonly associated with verapamil administration, making choices A, C, and D incorrect.