which of the following drugs is associated with the reaction of tendon dysfunction
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Nursing Elites

ATI RN

ATI Pharmacology Proctored

1. Which of the following drugs is associated with the reaction of tendon dysfunction?

Correct answer: D

Rationale: Fluoroquinolones are known to be associated with tendon dysfunction or rupture. These drugs can weaken the tendons, leading to potential issues such as tendonitis or even tendon rupture. It is essential for healthcare providers to be cautious when prescribing fluoroquinolones, especially in patients who may be at higher risk for tendon-related complications.

2. A client has a new prescription for a Nitroglycerin transdermal patch for Angina Pectoris. Which of the following instructions should the nurse include?

Correct answer: A

Rationale: The correct instruction for a client using a Nitroglycerin transdermal patch is to remove the patch each evening to prevent tolerance. This allows for a nitrate-free period of 10 to 12 hours during each 24-hour period, reducing the risk of developing tolerance to the medication. Choice B is incorrect because cutting the patch could alter the dose delivery and is not recommended. Choice C is incorrect as removing the patch for 30 minutes when a headache occurs may not be effective in managing symptoms. Choice D is incorrect as Nitroglycerin patches are usually applied once daily, not every 48 hours.

3. What is the appropriate medication to administer for a suspected opioid overdose in a patient who comes to the hospital?

Correct answer: B

Rationale: The correct answer is B: Naloxone. Naloxone is the drug of choice for managing opioid overdoses as it competitively antagonizes opioid receptors, reversing the respiratory depression and sedation caused by opioids. It is crucial in the emergency treatment of opioid overdose to prevent fatal outcomes. Choices A, C, and D are incorrect. Exenatide is a medication used to treat diabetes, heparin is an anticoagulant, and tolvaptan is a diuretic. None of these medications are indicated for the management of opioid overdose.

4. What is the therapeutic use of metformin?

Correct answer: C

Rationale: Metformin is commonly prescribed to manage and control blood glucose levels in individuals with diabetes. It helps in reducing the amount of glucose produced by the liver and improves the body's response to insulin, thereby aiding in the regulation of blood sugar levels. It is not used to lower blood pressure, diminish seizure activity, increase heart rate, or decrease gastrointestinal secretions.

5. A client has been prescribed a calcium channel blocker for angina. The nurse knows this medication should NOT be used with caution in combination with which drug classes?

Correct answer: C

Rationale: Calcium channel blockers and beta blockers should be used with caution together because they can both suppress heart function, potentially leading to bradycardia, heart block, or heart failure. NSAIDs and cardiac glycosides do not have significant interactions with calcium channel blockers in the same way, so they are not typically a cause for concern when combined.

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