ATI RN
ATI Pharmacology Proctored
1. Which of the following conditions are not treated with opioid analgesics like dextromethorphan and methadone?
- A. Pulmonary Edema
- B. Cough suppression
- C. Sedation
- D. Pain
Correct answer: C
Rationale: Opioid analgesics like dextromethorphan and methadone are primarily used for pain management and cough suppression. Sedation is not a primary indication for these medications.
2. What is the action of Nitroglycerin?
- A. Dilates the Bronchi
- B. Reduces Blood Glucose
- C. Reduces Nausea
- D. Dilates Coronary Arteries
Correct answer: D
Rationale: Nitroglycerin acts by dilating the coronary arteries, leading to increased blood flow and oxygen supply to the heart. This helps in relieving angina symptoms by reducing the heart's workload and improving blood supply to the myocardium. Choices A, B, and C are incorrect because Nitroglycerin's primary action is not related to dilating bronchi, reducing blood glucose, or reducing nausea.
3. A client with Hodgkin's disease is receiving Cyclophosphamide IV. Which medication should be administered concurrently to prevent an adverse effect of Cyclophosphamide?
- A. Uroprotectant agent, such as mesna
- B. Opioid, such as morphine
- C. Loop diuretic, such as furosemide
- D. H1 receptor antagonist, such as diphenhydramine
Correct answer: A
Rationale: Mesna, an uroprotectant agent, is administered with nitrogen mustard chemotherapy drugs like Cyclophosphamide to prevent hemorrhagic cystitis, a common adverse effect. Mesna works by binding to and inactivating the toxic metabolites of Cyclophosphamide in the bladder, thereby reducing the risk of bladder toxicity.
4. A client is receiving discharge instructions for a new prescription of Enoxaparin. Which of the following instructions should the provider include?
- A. Inject the medication into the muscle.
- B. Massage the injection site after administration.
- C. Rotate injection sites between the arms and thighs.
- D. Administer the medication in the abdomen.
Correct answer: D
Rationale: The correct answer is to administer the medication in the abdomen. Enoxaparin is administered as a subcutaneous injection in the abdomen to prevent bleeding complications. Injecting into the muscle or massaging the site can increase the risk of bleeding. Rotating sites between the arms and thighs is not recommended for Enoxaparin administration due to variations in absorption rates. Therefore, the provider should instruct the client to administer Enoxaparin in the abdomen for optimal effectiveness and safety.
5. A client has a new prescription for Lisinopril. Which of the following instructions should the nurse include?
- A. Avoid salt substitutes.
- B. Take this medication at bedtime.
- C. Increase your intake of potassium-rich foods.
- D. Take this medication with food.
Correct answer: A
Rationale: The correct instruction for a client prescribed Lisinopril is to avoid salt substitutes. Lisinopril, an ACE inhibitor, can lead to hyperkalemia, hence the importance of avoiding salt substitutes that may contain potassium. Instructing the client to avoid salt substitutes helps prevent potential adverse effects of increased potassium levels.
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