ATI RN
ATI Proctored Pharmacology Test
1. A client with HIV-1 infection is prescribed zidovudine as part of antiretroviral therapy. The nurse should monitor the client for which of the following adverse effects of this medication?
- A. Cardiac dysrhythmia
- B. Metabolic alkalosis
- C. Renal failure
- D. Aplastic anemia
Correct answer: D
Rationale: Corrected Rationale: Zidovudine is associated with the development of aplastic anemia, a serious adverse effect characterized by bone marrow suppression. Regular monitoring is essential to detect this side effect early and prevent complications. Cardiac dysrhythmia, metabolic alkalosis, and renal failure are not commonly associated with zidovudine use, making them incorrect choices for adverse effects of this medication.
2. A client has a new prescription for Ferrous sulfate. Which of the following instructions should be included?
- A. Take this medication with milk.
- B. Take this medication on an empty stomach.
- C. Take this medication before bedtime.
- D. Take this medication with antacids.
Correct answer: B
Rationale: The correct answer is B: 'Take this medication on an empty stomach.' Ferrous sulfate is best absorbed on an empty stomach. Instruct the client to take it 1 hour before or 2 hours after meals to maximize absorption and avoid interactions with food or beverages that may decrease absorption. Choice A is incorrect because taking Ferrous sulfate with milk can decrease its absorption. Choice C is incorrect as there is no specific benefit to taking it before bedtime. Choice D is incorrect as antacids can interfere with the absorption of Ferrous sulfate.
3. A hospitalized client has an activated partial thromboplastin time (aPTT) greater than 1.5 times the expected reference range. Which of the following blood products should be prepared for transfusion?
- A. Whole blood
- B. Platelets
- C. Fresh frozen plasma
- D. Packed red blood cells
Correct answer: C
Rationale: Fresh frozen plasma is the appropriate blood product for a client with an elevated aPTT as it contains various coagulation factors that can help correct coagulopathies and prevent bleeding. Elevated aPTT indicates a deficiency in specific clotting factors, and fresh frozen plasma is rich in these factors. Whole blood, platelets, and packed red blood cells do not contain the necessary coagulation factors to correct an elevated aPTT, so they are not indicated in this situation.
4. When teaching a client who has a prescription for Lisinopril, which of the following instructions should the nurse include?
- A. Take the medication at bedtime.
- B. Monitor for a persistent cough.
- C. Expect to have increased appetite.
- D. Avoid foods high in potassium.
Correct answer: B
Rationale: The correct answer is B: 'Monitor for a persistent cough.' Lisinopril, an ACE inhibitor, can cause a persistent dry cough as a side effect. It is essential for the client to report this symptom to their healthcare provider for further evaluation and management. Choice A is incorrect because Lisinopril is typically taken in the morning. Choice C is incorrect as Lisinopril is not known to cause increased appetite. Choice D is also incorrect as Lisinopril can lead to increased potassium levels in the blood, so avoiding foods high in potassium is not necessary.
5. Which of the following drugs is associated with extreme photosensitivity as a reaction?
- A. Digitalis
- B. Niacin
- C. Tetracycline
- D. Fluoroquinolones
Correct answer: C
Rationale: Tetracycline is known to cause extreme photosensitivity reactions, making individuals more sensitive to sunlight and increasing the risk of severe sunburn. It is essential for patients taking tetracycline to protect themselves from excessive sun exposure to prevent adverse reactions.
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