ATI RN
Proctored Pharmacology ATI
1. What is levothyroxine's pharmacologic classification?
- A. Thyroid Preparations
- B. Metabolic Inhibitors
- C. Analgesic
- D. Loop Diuretic
Correct answer: A
Rationale: Levothyroxine is classified as a thyroid preparation because it is a synthetic form of the thyroid hormone thyroxine. It is primarily used to treat hypothyroidism by supplementing or replacing the natural thyroid hormones in the body, helping to regulate metabolism and energy levels. Choice B, Metabolic Inhibitors, is incorrect because levothyroxine does not inhibit metabolism but rather helps regulate it. Choice C, Analgesic, is incorrect as levothyroxine is not used for pain relief but for thyroid hormone replacement therapy. Choice D, Loop Diuretic, is also incorrect as loop diuretics are medications that act on the kidneys to increase urine production and are not related to thyroid hormone replacement therapy.
2. What is the action of Metformin?
- A. Decreasing intestinal glucose absorption
- B. Increasing sensitivity to insulin
- C. Decreasing hepatic glucose production
- D. All of the above
Correct answer: D
Rationale: Metformin exerts its effects by decreasing hepatic glucose production, increasing sensitivity to insulin, and decreasing intestinal glucose absorption. These actions help in lowering blood glucose levels and improving insulin sensitivity in individuals with diabetes.
3. A client receiving chemotherapy with Methotrexate asks why Leucovorin is being given. Which of the following responses should the nurse use?
- A. Leucovorin reduces the risk of a transfusion reaction from Methotrexate.
- B. Leucovorin increases platelet production and prevents bleeding.
- C. Leucovorin potentiates the cytotoxic effects of Methotrexate.
- D. Leucovorin protects healthy cells from Methotrexate's toxic effects.
Correct answer: D
Rationale: Leucovorin, a folic acid derivative and an antagonist to Methotrexate, is given within 12 hours of high doses of Methotrexate to protect healthy cells from the toxic effects of Methotrexate. It helps to reduce the bone marrow suppression and gastrointestinal side effects caused by Methotrexate, supporting the client's overall well-being during chemotherapy treatment. Choices A, B, and C are incorrect because Leucovorin does not reduce the risk of a transfusion reaction from Methotrexate, increase platelet production, prevent bleeding, or potentiate the cytotoxic effects of Methotrexate. Instead, Leucovorin works by rescuing healthy cells from the toxic effects of Methotrexate.
4. A client has a prescription for a Nicotine transdermal patch. Which of the following instructions should the nurse include?
- A. Apply the patch at the same time each day.
- B. Remove the patch at bedtime.
- C. Apply the patch to the same location daily.
- D. Place the patch over an area of the body with hair.
Correct answer: A
Rationale: The correct instruction for a client using a Nicotine transdermal patch is to apply the patch at the same time each day. This helps maintain consistent blood levels of nicotine throughout the treatment period, which can aid in reducing cravings for smoking. Consistency in the application time is essential for the effectiveness of the patch. Choices B, C, and D are incorrect. Removing the patch at bedtime may disrupt the continuous delivery of nicotine, applying the patch to the same location daily can cause skin irritation, and placing the patch over an area with hair may affect its adhesion and absorption.
5. A healthcare professional is reviewing the laboratory results of a client who is taking Lithium for Bipolar Disorder. Which of the following findings should the healthcare professional report to the provider immediately?
- A. Lithium level of 1.0 mEq/L
- B. Potassium level of 3.5 mEq/L
- C. Sodium level of 140 mEq/L
- D. Creatinine level of 1.0 mg/dL
Correct answer: D
Rationale: A creatinine level of 1.0 mg/dL should be reported to the provider immediately. While a lithium level of 1.0 mEq/L falls within the therapeutic range, a creatinine level of 1.0 mg/dL could suggest early signs of kidney dysfunction, especially concerning in a client on long-term lithium therapy. It is crucial to monitor kidney function closely because lithium can be nephrotoxic over time. Elevated creatinine levels may indicate impaired kidney function and should prompt immediate reporting to the healthcare provider. Potassium and sodium levels within normal range are not immediate concerns when compared to potential kidney issues.
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