ATI RN
Pathophysiology Practice Questions
1. Which pathophysiologic process causes the decreased glomerular filtration rate in a patient with acute glomerulonephritis?
- A. Decreased renal-induced constriction of the renal arteries
- B. Immune complex deposition, increased capillary permeability, and cellular proliferation
- C. Necrosis of 70% or more of the nephrons secondary to increased kidney interstitial hydrostatic pressure
- D. Scar tissue formation throughout the proximal convoluted tubule secondary to toxin-induced collagen synthesis
Correct answer: B
Rationale: The correct answer is B: Immune complex deposition, increased capillary permeability, and cellular proliferation. In acute glomerulonephritis, immune complexes deposit in the glomerulus, leading to inflammation, increased capillary permeability, and cellular proliferation. These processes collectively reduce the glomerular filtration rate. Choices A, C, and D do not accurately describe the pathophysiologic process in acute glomerulonephritis. Decreased renal-induced constriction of the renal arteries, necrosis of nephrons due to increased kidney interstitial hydrostatic pressure, and scar tissue formation in the proximal convoluted tubule are not the primary mechanisms responsible for the decreased filtration rate in this condition.
2. A nurse is providing dietary teaching to the parent of a school-age child with cystic fibrosis. Which of the following statements should the nurse make?
- A. You should offer your child high-protein meals and snacks throughout the day
- B. Your child should decrease dietary fats to less than 10% of their caloric intake
- C. Your child will need to take a 1-gram sodium chloride tablet daily throughout their lifetime
- D. You should calculate your child's carbohydrate needs based on their daily activities
Correct answer: A
Rationale: The parent should provide a well-balanced diet that is high in protein and calories for a child with cystic fibrosis. This diet helps meet the child's increased energy requirements. Offering high-protein meals and snacks throughout the day is essential to ensure adequate nutrition and energy intake for children with cystic fibrosis. Choices B, C, and D are incorrect because children with cystic fibrosis actually need a higher fat intake for proper absorption of fat-soluble vitamins, sodium chloride supplementation is not a general recommendation for all children with cystic fibrosis, and carbohydrate needs are usually based on maintaining adequate weight and growth rather than daily activities.
3. A patient is receiving glucocorticoids for the treatment of rheumatoid arthritis. The patient complains of having a headache. Which ordered medication should the nurse administer?
- A. Aspirin
- B. Acetaminophen
- C. Ibuprofen
- D. Naproxen Sodium (Aleve)
Correct answer: B
Rationale: When a patient is already receiving glucocorticoids for rheumatoid arthritis and complains of a headache, it is essential to consider the potential interactions and side effects of additional medications. Aspirin and NSAIDs like ibuprofen and naproxen sodium can increase the risk of gastrointestinal irritation and ulceration when used concurrently with glucocorticoids. Acetaminophen is a safer choice in this scenario for managing the patient's headache without exacerbating the gastrointestinal issues associated with the use of glucocorticoids. Acetaminophen does not have the same gastrointestinal side effects as aspirin, ibuprofen, or naproxen sodium, making it the most appropriate option for headache relief in this case.
4. What physiologic role does magnesium play in the body?
- A. Blood clotting, transmission of nerve impulses, muscle contraction and relaxation
- B. Calcium homeostasis, structural integrity of heart muscle
- C. No known metabolic function, caries-preventing properties
- D. ATP energy release; metabolism of fats, carbohydrates, proteins; regulates acid-base balance
Correct answer: B
Rationale: The correct answer is B. Magnesium plays an important role in maintaining calcium homeostasis and preventing skeletal abnormalities. It is involved in more than 300 enzymatic reactions, including energy metabolism, insulin activity, and glucose use. Magnesium is vital to the structural integrity of heart muscle and other muscles and nerves. While magnesium does play a role in blood clotting, nerve impulses, muscle contraction, relaxation, ATP energy release, and metabolism of fats, carbohydrates, proteins, the primary physiologic role of magnesium in the body is related to calcium homeostasis and maintaining the structural integrity of the heart muscle. Choice A is incorrect because it includes functions of magnesium, but they are not its primary physiologic role. Choice C is incorrect as magnesium has several known metabolic functions. Choice D is incorrect because although magnesium is involved in ATP energy release and metabolism, its primary role is related to calcium homeostasis and structural integrity of muscle.
5. What is the primary focus of transitional care?
- A. To improve clinical outcomes
- B. To manage chronic diseases
- C. To facilitate smooth transitions between care settings
- D. To support family caregivers
Correct answer: C
Rationale: The primary focus of transitional care is to facilitate smooth transitions between care settings. While improving clinical outcomes and managing chronic diseases are important aspects of healthcare, the main goal of transitional care is to ensure patients move smoothly between different care settings such as hospitals, rehabilitation centers, and home care. Supporting family caregivers is also essential but not the primary focus of transitional care.
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