ATI RN
Pharmacology ATI Proctored Exam 2023
1. Reteplase (Retavase) has been ordered for a client diagnosed with an MI. The nurse understands that this drug needs to be administered within which time frame following the onset of symptoms?
- A. 45 minutes to 18 hours
- B. 30 minutes to 12 hours
- C. 90 minutes to 36 hours
- D. 60 minutes to 24 hours
Correct answer: B
Rationale: Reteplase (Retavase) is a thrombolytic medication used in the treatment of myocardial infarction (MI). It is crucial to administer this drug within 30 minutes to 12 hours following the onset of symptoms to achieve optimal therapeutic effects and improve patient outcomes. Administering Reteplase within this time frame helps in restoring blood flow to the affected areas of the heart by dissolving blood clots, reducing myocardial damage, and potentially preventing further complications associated with MI.
2. Following a stroke, a client has been started on clopidogrel (Plavix). Why is this medication being administered?
- A. To prevent stroke in high-risk patients, such as those with prosthetic heart valves
- B. To decrease blood pressure
- C. To increase heart rate
- D. To provide antiplatelet activity in patients who cannot tolerate aspirin
Correct answer: D
Rationale: Clopidogrel (Plavix) is an antiplatelet medication that inhibits platelet aggregation, reducing the risk of blood clots. It is commonly used in patients who have had a stroke and cannot tolerate aspirin due to allergies or intolerances. Choosing clopidogrel in these cases helps prevent further clot formation and reduces the risk of recurrent strokes.
3. What is the pharmacological class of Lithium?
- A. Antidiabetics, biguanides
- B. Mood stabilizers
- C. Antiarrhythmics, anticonvulsants
- D. Vascular headache suppressants
Correct answer: B
Rationale: Lithium is classified as a mood stabilizer due to its primary use in managing bipolar disorder, where it helps stabilize mood swings and prevent episodes of mania and depression. While it can have other effects on the body, its main therapeutic role lies in its mood-stabilizing properties. Choices A, C, and D are incorrect as lithium is not classified as antidiabetics, biguanides, antiarrhythmics, anticonvulsants, or vascular headache suppressants. Its main pharmacological class is mood stabilizers.
4. A healthcare professional is caring for a client who has a new prescription for Lisinopril. Which of the following laboratory values should the professional monitor?
- A. Serum potassium
- B. Serum sodium
- C. Serum calcium
- D. Serum magnesium
Correct answer: A
Rationale: Lisinopril is an ACE inhibitor that can cause hyperkalemia by reducing the excretion of potassium in the kidneys. Monitoring serum potassium levels is essential to prevent complications such as cardiac arrhythmias. Therefore, the healthcare professional should closely monitor the client's serum potassium levels when they are on Lisinopril. Choices B, C, and D are incorrect because Lisinopril primarily affects potassium levels due to its mechanism of action as an ACE inhibitor. Serum sodium, calcium, and magnesium levels are not typically affected by Lisinopril in the same way as potassium.
5. A client has a new prescription for Omeprazole. Which of the following statements should the nurse include in teaching the client?
- A. Take the medication before meals.
- B. You may experience a rapid heart rate.
- C. Increase your intake of high-calcium foods.
- D. Expect your urine to turn orange.
Correct answer: A
Rationale: The correct statement for the nurse to include when teaching a client prescribed Omeprazole is to take the medication before meals. Omeprazole, a proton pump inhibitor, is most effective when taken before meals as it works by reducing the amount of acid produced in the stomach. Choice B is incorrect because a rapid heart rate is not a common side effect of Omeprazole. Choice C is incorrect as there is no specific requirement to increase intake of high-calcium foods with Omeprazole. Choice D is also incorrect as Omeprazole does not typically cause urine discoloration.
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