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ATI Pharmacology Test Bank
1. Why does a nurse on an oncology unit verify a client's current cumulative lifetime dose of doxorubicin before administering it to a client with breast cancer?
- A. Excessive doxorubicin can result in myelosuppression.
- B. Exceeding the lifetime cumulative dose limit of doxorubicin may lead to extravasation.
- C. An excess amount of doxorubicin can lead to cardiomyopathy.
- D. Exceeding the lifetime cumulative dose limit of doxorubicin may cause red-tinged urine and sweat.
Correct answer: C
Rationale: Verifying the client's current cumulative lifetime dose of doxorubicin is necessary because excessive amounts of the medication can lead to cardiomyopathy, a serious and potentially life-threatening side effect. By monitoring the cumulative dose, healthcare providers can help prevent cardiotoxicity and ensure patient safety during treatment.
2. A client with active tuberculosis asks why he must take four different medications. Which of the following responses should the nurse make?
- A. Taking four medications decreases the risk of a severe allergic reaction.
- B. Taking four medications reduces the chance that the bacteria will become resistant.
- C. Taking four medications reduces the risk of adverse reactions.
- D. Taking four medications decreases the chance of having a positive tuberculin skin test.
Correct answer: B
Rationale: When treating tuberculosis, using a combination of multiple medications is crucial to reduce the risk of bacterial resistance. The use of four medications helps to target the bacteria from different angles, making it harder for them to develop resistance to the treatment. This approach is essential to ensure the effectiveness of the treatment regimen and to prevent the spread of drug-resistant strains of tuberculosis. Choices A, C, and D are incorrect because the primary reason for using multiple medications in tuberculosis treatment is to prevent the development of bacterial resistance, not to decrease the risk of allergic reactions, adverse reactions, or affecting the tuberculin skin test results.
3. Which of the following conditions is not treated with Dexamethasone?
- A. Inflammation
- B. Asthma
- C. Addison’s disease
- D. Wilson’s disease
Correct answer: D
Rationale: Dexamethasone is not used to treat Wilson’s disease. It is a corticosteroid primarily used for conditions like inflammation, asthma, and Addison’s disease. Wilson’s disease is a genetic disorder involving copper accumulation and is treated with medications like chelating agents or zinc salts, not Dexamethasone.
4. A client has a new prescription for Prednisone. Which of the following instructions should be included in the discharge teaching?
- A. Increase your intake of potassium-rich foods.
- B. Avoid consuming grapefruit juice.
- C. Take this medication with food.
- D. Decrease your intake of sodium-rich foods.
Correct answer: A
Rationale: The correct answer is A: 'Increase your intake of potassium-rich foods.' Prednisone can lead to potassium depletion, making it important for clients to increase their intake of potassium-rich foods like bananas, oranges, and spinach to prevent potential complications. Choice B is incorrect because grapefruit juice can interact with certain medications, but it is not a specific concern with Prednisone. Choice C is incorrect as Prednisone can be taken with or without food. Choice D is also incorrect because there is no direct relationship between Prednisone and sodium-rich foods.
5. A client has a new prescription for Atenolol. Which of the following instructions should the nurse provide?
- A. Take this medication with grapefruit juice.
- B. Monitor your blood pressure and heart rate regularly.
- C. You may experience a rapid heart rate.
- D. Increase your intake of potassium-rich foods.
Correct answer: B
Rationale: The correct answer is B: 'Monitor your blood pressure and heart rate regularly.' Atenolol is a beta-blocker used to treat hypertension and other cardiovascular conditions. Patients should monitor their blood pressure and heart rate regularly to assess the medication's effectiveness and check for adverse effects like bradycardia or hypotension. Choice A is incorrect because Atenolol should not be taken with grapefruit juice, which can interfere with its absorption. Choice C is incorrect because Atenolol typically causes a decrease in heart rate, not a rapid heart rate. Choice D is incorrect because there is no specific need to increase potassium-rich foods while taking Atenolol.
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