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MSN 570 Advanced Pathophysiology Final 2024
1. What is the primary cause of primary hypercholesteremia?
- A. High-density lipoprotein (HDL) defects
- B. Monogenic mutations, sedentary lifestyle, and high cholesterol diet
- C. Polygenic mutations and environmental factors
- D. Low-density lipoprotein (LDL) receptor mutation with defects in breakdown
Correct answer: D
Rationale: The correct answer is 'Low-density lipoprotein (LDL) receptor mutation with defects in breakdown.' Primary hypercholesteremia is mainly caused by mutations in the LDL receptor, leading to impaired clearance of LDL cholesterol from the blood. This results in high levels of LDL cholesterol in the bloodstream. Choices A, B, and C are incorrect because they do not directly relate to the primary cause of primary hypercholesteremia.
2. Which of the following characteristics is common in both malignant and benign tumors?
- A. Uncontrolled cell growth
- B. Rapid growth
- C. Metastasis
- D. Invasion of surrounding tissue
Correct answer: A
Rationale: The correct answer is A: Uncontrolled cell growth. This characteristic is common to both malignant and benign tumors. Benign tumors are non-cancerous growths that do not invade nearby tissue or spread to other parts of the body. Therefore, choices B, C, and D are incorrect. Rapid growth, metastasis, and invasion of surrounding tissue are characteristics typically associated with malignant tumors.
3. A patient is starting on atorvastatin (Lipitor) for hyperlipidemia. What important instruction should the nurse provide?
- A. Take the medication at night to reduce the risk of muscle pain.
- B. Avoid consuming grapefruit juice while taking this medication.
- C. Take the medication in the morning with breakfast.
- D. Avoid taking the medication with alcohol to reduce the risk of liver damage.
Correct answer: A
Rationale: The correct answer is A. Atorvastatin should be taken at night to reduce the risk of muscle pain and other side effects. Taking it at night aligns with the body's natural rhythm of cholesterol production, optimizing its effectiveness. Choice B is incorrect because grapefruit juice can increase the risk of side effects by affecting the metabolism of atorvastatin. Choice C is incorrect as taking atorvastatin in the morning does not maximize its effectiveness. Choice D is incorrect because alcohol consumption can increase the risk of liver damage when combined with atorvastatin.
4. Which of the following describes the type of incontinence due to an increase in intraabdominal pressure such as coughing, sneezing, and laughing?
- A. Overflow
- B. Stress
- C. Mixed
- D. Functional
Correct answer: B
Rationale: The correct answer is B: Stress. Stress incontinence occurs when there is an increase in intraabdominal pressure, for example, during activities like coughing, sneezing, or laughing, leading to urine leakage. This type of incontinence is specifically triggered by physical movements or activities that put pressure on the bladder. Choices A, C, and D are incorrect because overflow incontinence is characterized by the bladder not emptying properly, mixed incontinence is a combination of stress and urge incontinence, and functional incontinence is typically due to physical or cognitive impairments.
5. What is the purpose of the inflammatory response?
- A. Prevents blood from entering the injured tissue
- B. Elevates body temperature to prevent spread of infection
- C. Prevents formation of abscess
- D. Minimizes injury and promotes healing
Correct answer: D
Rationale: The inflammatory response is a protective mechanism triggered by tissue damage or infection. It aims to minimize injury by removing harmful stimuli and initiating the healing process. Choice A is incorrect because blood flow to the injured tissue is actually increased to deliver immune cells and nutrients. Choice B is incorrect because while fever is a response to infection, it is not the primary purpose of the inflammatory response. Choice C is incorrect because abscess formation can occur as part of the inflammatory response in an attempt to contain an infection.
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