ATI RN
ATI Pathophysiology Exam 1
1. In addition to matching ABO antigens, a blood transfusion must also be matched for:
- A. HLA type
- B. Rh antigen
- C. Immunoglobulins
- D. Platelet compatibility
Correct answer: B
Rationale: The correct answer is B: Rh antigen. In addition to ABO antigens, Rh antigen must also be matched for a blood transfusion. Rh antigen compatibility is crucial to prevent adverse reactions. Choice A, HLA type, is not directly related to blood transfusions but plays a role in organ transplantation. Choice C, Immunoglobulins, are not typically matched for blood transfusions. Choice D, Platelet compatibility, while important in specific cases, is not a standard requirement for all blood transfusions.
2. Which of the following statements describes an active cellular membrane exchange process?
- A. Sodium moving out of cells and potassium moving into cells
- B. The movement of water from an area of low solute concentration to an area of high solute concentration
- C. The movement of insulin using a protein to travel across the cell membrane
- D. Oxygen moving across the pulmonary capillaries to an area of high carbon dioxide
Correct answer: A
Rationale: The correct answer is A. In active transport, energy is expended to move substances against their concentration gradient. Sodium moving out of cells and potassium moving into cells is an example of active transport because it requires energy to pump these ions across the cell membrane against their concentration gradients. Choices B, C, and D describe passive processes where substances move along their concentration gradients without the input of energy.
3. A patient is being treated for a severe fungal infection with amphotericin B. What is the expected length of treatment for this patient?
- A. 1 to 2 weeks
- B. 3 to 6 weeks
- C. 4 to 12 weeks
- D. 15 to 18 weeks
Correct answer: C
Rationale: The correct answer is C: '4 to 12 weeks.' Amphotericin B treatment duration for severe fungal infections typically ranges from 4 to 12 weeks. This extended period is necessary to ensure complete eradication of the fungal infection and prevent relapse. Choices A, B, and D provide durations that are either too short or too long for treating severe fungal infections effectively, making them incorrect.
4. Which immunoglobulin is the first to appear in response to a new antigen?
- A. IgA
- B. IgG
- C. IgE
- D. IgM
Correct answer: D
Rationale: The correct answer is IgM. IgM is the first immunoglobulin to appear in response to a new antigen. It is produced initially during the primary immune response. IgA is mainly found in mucosal areas and secretions. IgG is produced in a secondary immune response and is the most abundant immunoglobulin in the bloodstream. IgE is involved in allergic reactions and parasitic infections, not the initial response to a new antigen.
5. A client with a history of hypertension presents with a severe headache and blurred vision. What is the nurse's priority action?
- A. Administer pain relief medication.
- B. Obtain a stat head CT scan.
- C. Administer antihypertensive medications as prescribed.
- D. Call the healthcare provider immediately.
Correct answer: C
Rationale: The correct answer is to administer antihypertensive medications as prescribed. In a client with a history of hypertension presenting with severe headache and blurred vision, these symptoms could indicate a hypertensive crisis. The priority action is to lower the blood pressure promptly to prevent complications such as stroke, heart attack, or organ damage. Administering antihypertensive medications is crucial in this situation. Administering pain relief medication (Choice A) may temporarily alleviate symptoms but does not address the underlying issue of elevated blood pressure. Obtaining a stat head CT scan (Choice B) may be necessary to rule out other causes but should not delay the administration of antihypertensive medications. Calling the healthcare provider immediately (Choice D) is important but may not address the immediate need to lower blood pressure in a hypertensive crisis.
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