Nursing Elites

1. An experiment is designed to determine specific cell types involved in cell-mediated immune response. The experimenter is interested in finding cells that attack cells that have specific antigens. Which cells should be isolated?

• A. Lymphokine-producing cells
• B. Cytotoxic T cells
• C. Helper T cells
• D. Macrophages

Correct answer: B

Rationale: Cytotoxic T cells are the key players in cell-mediated immunity as they directly attack cells displaying specific antigens. Lymphokine-producing cells (Choice A) are involved in cytokine production, while Helper T cells (Choice C) assist in activating other immune cells. Macrophages (Choice D) are phagocytic cells that engulf and digest pathogens, but they are not the primary cells responsible for directly attacking cells with specific antigens in cell-mediated immunity.

2. An infant is being administered an immunization. Which of the following provides an accurate description of an immunization?

• A. It should be administered to a pregnant woman prior to the infant's birth.
• B. It is the administration of an antigen to stimulate an antibody response.
• C. It produces many adverse reactions, particularly autism, in the infant.
• D. It protects the infant from exposure to infectious antibodies.

Correct answer: B

Rationale: The correct answer is B. Immunization involves administering an antigen, such as a weakened or killed microorganism, to stimulate the immune system to produce an antibody response. This process helps the body recognize and remember specific pathogens, providing immunity against future infections. Choice A is incorrect because immunizations are administered to the infant directly, not to the pregnant woman before birth. Choice C is incorrect as there is no scientific evidence linking immunizations to autism. Choice D is incorrect as immunizations protect against infectious agents, not antibodies.

3. Which of the following is a clinical manifestation of hyperthyroidism?

• A. Tachycardia
• B. Constipation
• C. Weight gain
• D. Fatigue

Correct answer: A

Rationale: The correct answer is A: Tachycardia. Tachycardia, which is an increased heart rate, is a classic clinical manifestation of hyperthyroidism. In hyperthyroidism, there is an excess production of thyroid hormones, leading to an increased metabolic rate. This increased metabolism can cause symptoms such as a rapid heart rate. Choices B, C, and D are incorrect because constipation, weight gain, and fatigue are more commonly associated with hypothyroidism, where there is a deficiency of thyroid hormones leading to a slower metabolic rate.

4. In which of the following patients may the administration of a live vaccine be contraindicated?

• A. Patient with renal insufficiency
• B. Patient with hepatic failure
• C. Patient taking steroid therapy
• D. Patient over the age of 65 years

Correct answer: C

Rationale: The correct answer is C. The administration of live vaccines may be contraindicated in patients taking steroid therapy. Steroids can suppress the immune system, reducing the effectiveness of live vaccines. Patients with renal insufficiency or hepatic failure can typically receive live vaccines as these conditions are not direct contraindications. Age alone, such as being over 65 years old, is not a contraindication for live vaccines unless there are other specific health considerations. Therefore, the patient taking steroid therapy is the most likely candidate for whom the administration of a live vaccine would be contraindicated.

5. A patient with systemic candidiasis has been prescribed flucytosine. The nurse should be aware of the need to administer this drug with which of the following?

• A. Vitamin D and calcium supplements
• B. Fluconazole (Diflucan)
• C. Amphotericin B
• D. Penicillin G

Correct answer: C

Rationale: The correct answer is C: Amphotericin B. When treating systemic candidiasis, Amphotericin B is the drug of choice, not flucytosine. Amphotericin B is an antifungal medication used to treat severe fungal infections like systemic candidiasis. Choices A, B, and D are incorrect because vitamin D and calcium supplements, fluconazole, and penicillin G are not the drugs of choice for treating systemic candidiasis.

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