ATI RN
Pathophysiology Final Exam
1. An 8-year-old boy has been diagnosed with a sex hormone deficiency and has begun a course of treatment with testosterone. What change in the boy's health status would necessitate a stop to the course of treatment?
- A. Excessive growth in height
- B. Signs of puberty
- C. Recurrent urinary tract infections
- D. Increased blood pressure
Correct answer: B
Rationale: In an 8-year-old boy with a sex hormone deficiency being treated with testosterone, the appearance of signs of puberty would necessitate stopping the treatment. Testosterone therapy in this case aims to supplement the deficient sex hormones but should not trigger premature puberty. Excessive growth in height (choice A) is not a typical reason to stop testosterone therapy. Recurrent urinary tract infections (choice C) and increased blood pressure (choice D) are not directly related to testosterone therapy in this context.
2. A 22-year-old was recently diagnosed with acquired immunodeficiency syndrome (AIDS). Which decreased lab finding would be expected to accompany this virus?
- A. CD4 helper T cells
- B. CD8 helper T cells
- C. CDC cells
- D. CDC10 cells
Correct answer: A
Rationale: In a person diagnosed with AIDS, a decrease in CD4 helper T cells is expected. These cells are critical for the immune system's proper functioning, and their reduction weakens the body's ability to fight infections. CD8 helper T cells (Choice B) are not typically decreased in AIDS. CDC cells (Choice C) and CDC10 cells (Choice D) are not relevant terms in this context, making them incorrect choices.
3. A patient with a history of osteoporosis is prescribed raloxifene (Evista). What is the primary therapeutic action of this medication?
- A. It stimulates the formation of new bone.
- B. It decreases bone resorption and increases bone density.
- C. It increases calcium absorption in the intestines.
- D. It increases the excretion of calcium through the kidneys.
Correct answer: B
Rationale: The correct answer is B: 'It decreases bone resorption and increases bone density.' Raloxifene, as a selective estrogen receptor modulator (SERM), works by reducing bone resorption (breakdown) and maintaining or increasing bone density. This mechanism helps in preventing further bone loss and can even increase bone mass. Choices A, C, and D are incorrect. Raloxifene does not stimulate the formation of new bone (choice A), increase calcium absorption in the intestines (choice C), or increase the excretion of calcium through the kidneys (choice D).
4. In chronic obstructive pulmonary disease, the inflammatory response predominantly involves:
- A. eosinophils
- B. neutrophils
- C. monocytes
- D. cells
Correct answer: B
Rationale: In chronic obstructive pulmonary disease, the inflammatory response predominantly involves neutrophils. Neutrophils play a key role in COPD due to their involvement in initiating and sustaining the inflammatory process. Eosinophils are more commonly associated with asthma rather than COPD. Monocytes are less involved in the inflammatory response in COPD compared to neutrophils. The choice 'cells' is too broad and vague to be a specific answer in this context.
5. A client has been admitted to the hospital with symptoms of Guillain-Barré syndrome. Which aspect of the client's condition would require priority monitoring?
- A. Monitoring oxygen saturation levels
- B. Monitoring for signs of respiratory compromise
- C. Monitoring for changes in consciousness
- D. Monitoring blood pressure closely
Correct answer: B
Rationale: In Guillain-Barré syndrome, respiratory muscle weakness can lead to respiratory compromise, making it crucial to prioritize monitoring for signs of respiratory distress. Monitoring oxygen saturation levels is important but is secondary to assessing for respiratory compromise in this condition. Changes in consciousness and monitoring blood pressure closely are not typically the priority in Guillain-Barré syndrome.
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