ATI RN
ATI Pathophysiology Exam 1
1. What is the major effect of filgrastim (Neupogen) in a patient with chronic renal failure?
- A. Decreases neutropenia related to chemotherapy
- B. Decreases white blood cells related to infection
- C. Decreases growth of blood vessels due to ischemia
- D. Decreases platelet count related to bleeding
Correct answer: A
Rationale: The major effect of filgrastim (Neupogen) is to stimulate the production of neutrophils, thereby decreasing neutropenia in patients undergoing chemotherapy. This medication helps the bone marrow produce more white blood cells, specifically neutrophils, to reduce the risk of infections associated with low neutrophil counts. Choices B, C, and D are incorrect because filgrastim does not decrease white blood cells related to infection, growth of blood vessels, or platelet count related to bleeding.
2. A client has a new prescription for heparin therapy. Which of the following statements by the client should indicate an immediate concern for the nurse?
- A. ''I am allergic to morphine.''
- B. ''I take antacids several times a day.''
- C. ''I had a blood clot in my leg several years ago.''
- D. ''It hurts to take a deep breath.''
Correct answer: ''I take antacids several times a day.''
Rationale: The correct answer is the statement 'I take antacids several times a day.' Antacids can alter the absorption of heparin, potentially affecting its effectiveness and increasing the risk of clot formation. This is a significant concern as it can impact the therapeutic outcome of heparin therapy. The other statements are not directly related to potential complications or interactions with heparin therapy.
3. A nurse is preparing to administer furosemide to a client. Which of the following findings indicates the client may be at risk for an adverse effect of the medication?
- A. Hypertension
- B. Hypokalemia
- C. Increased urine output
- D. Hyperglycemia
Correct answer: B
Rationale: The correct answer is B: Hypokalemia. Furosemide is a loop diuretic that can cause potassium depletion, leading to hypokalemia, which is a common adverse effect. Hypokalemia can result in serious complications like cardiac arrhythmias. Choices A, C, and D are not directly associated with the adverse effects of furosemide. Hypertension is a condition that furosemide is often used to treat, increased urine output is an expected effect of furosemide, and hyperglycemia is not a typical adverse effect of this medication.
4. What is the digestive action of bile?
- A. It breaks down carbohydrates
- B. It breaks down proteins
- C. It breaks down lipids
- D. It aids in fat digestion
Correct answer: D
Rationale: Bile, which is produced by the liver and stored in the gallbladder, aids in the digestion of fats. It does this by emulsifying the fats, which makes them easier for the digestive enzymes, such as lipase, to break down. While choices A, B, and C could be seen as partially correct since fats are a type of lipid and the process of breaking down fats could be seen as breaking down lipids, the most accurate answer is D, as the primary function of bile is to aid in fat digestion, not the digestion of all types of lipids or the digestion of proteins or carbohydrates.
5. After a subtotal gastrectomy, care of the client’s nasogastric tube and drainage system should include which of the following nursing interventions?
- A. Irrigate the tube with 30 ml of sterile water every hour, if needed.
- B. Reposition the tube if it is not draining well
- C. Monitor the client for N/V, and abdominal distention
- D. Turn the machine to high suction of the drainage is sluggish on low suction.
Correct answer: C
Rationale: Monitoring the client for nausea, vomiting, and abdominal distention is crucial for ensuring proper functioning of the nasogastric tube and drainage system.
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