ATI RN
ATI Pathophysiology Test Bank
1. A patient who is undergoing treatment for cytomegalovirus received his first dose of IV ganciclovir 3 days ago. When reviewing this patient's most recent blood work, what abnormality should the nurse most likely attribute to the use of this drug?
- A. Hemoglobin 17 g/dL (high normal)
- B. INR 3.8 (high)
- C. Platelet count 118,000/mm3 (low)
- D. Leukocytes 11,900/mm3 (high)
Correct answer: C
Rationale: The correct answer is C: Platelet count 118,000/mm3 (low). Ganciclovir, used to treat cytomegalovirus, is known to cause bone marrow suppression, leading to decreased platelet count (thrombocytopenia). This condition can increase the risk of bleeding. Choices A, B, and D are not typically associated with ganciclovir therapy. High hemoglobin levels (choice A) are not commonly seen with ganciclovir treatment. INR elevation (choice B) is associated with coagulation abnormalities, which are not a typical side effect of ganciclovir. Elevated leukocyte count (choice D) is not a common consequence of ganciclovir use.
2. Thrombocytopenia is which disorder below?
- A. Increased blood coagulation
- B. Increased platelet production
- C. Increased number of infections
- D. Decreased platelet production
Correct answer: D
Rationale: Thrombocytopenia is a disorder characterized by a decreased platelet count or decreased platelet production, which affects blood clotting. Choice A, 'Increased blood coagulation,' is incorrect as thrombocytopenia is associated with decreased platelets, leading to impaired clotting. Choice B, 'Increased platelet production,' is incorrect as thrombocytopenia is characterized by a decrease in platelet production. Choice C, 'Increased number of infections,' is unrelated to thrombocytopenia, which primarily involves low platelet levels.
3. A patient is prescribed medroxyprogesterone acetate (Provera) for the treatment of endometriosis. What key instruction should the nurse provide regarding the use of this medication?
- A. Take the medication at the same time each day to maintain consistent hormone levels.
- B. Medroxyprogesterone should be taken with food to reduce gastrointestinal upset.
- C. Medroxyprogesterone should be discontinued if side effects occur.
- D. Medroxyprogesterone should be taken once a week to maintain effectiveness.
Correct answer: A
Rationale: The correct instruction the nurse should provide regarding the use of medroxyprogesterone acetate (Provera) for endometriosis is to take the medication at the same time each day. This helps to maintain consistent hormone levels and ensures the effectiveness of the treatment. Choice B is incorrect because medroxyprogesterone should be taken without regard to meals. Choice C is incorrect because side effects should be reported to the healthcare provider for evaluation rather than discontinuing the medication without medical advice. Choice D is incorrect as medroxyprogesterone is usually taken daily, not weekly, for the treatment of endometriosis.
4. After a 27-year-old woman with epilepsy had a generalized seizure, she feels tired and falls asleep. This is:
- A. an ominous sign.
- B. normal and termed the postictal period.
- C. a reflection of an underlying brain tumor.
- D. only worrisome if there are focal neurologic deficits after.
Correct answer: B
Rationale: The correct answer is B: normal and termed the postictal period. The postictal period is a common phase following a seizure where the individual may experience fatigue, confusion, or sleepiness. It is a normal part of the seizure event and does not necessarily indicate a serious issue. Choice A is incorrect because feeling tired and falling asleep after a seizure is not an ominous sign but rather a typical postictal symptom. Choice C is incorrect as there is no indication in the scenario provided that links the symptoms to an underlying brain tumor. Choice D is incorrect because the absence of focal neurologic deficits does not make the postictal period worrisome.
5. What important instruction should the nurse provide regarding the application of testosterone gel in a patient with hypogonadism?
- A. Apply the gel to the chest or upper arms and allow it to dry completely before dressing.
- B. Apply the gel to the face and neck for maximum absorption.
- C. Apply the gel to the genitals for improved results.
- D. Apply the gel to the scalp and back for better results.
Correct answer: A
Rationale: The correct instruction for applying testosterone gel in a patient with hypogonadism is to apply it to the chest or upper arms and allow it to dry completely before dressing. This method helps avoid transfer to others. Applying the gel to the face, neck, or genitals is not recommended as it can lead to unintended exposure to others. Additionally, applying the gel to the scalp and back is not a standard or effective route of administration for testosterone gel. Therefore, choice A is the correct answer as it ensures proper application and safety.
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