a patient is starting on a statin medication for hyperlipidemia what critical instruction should the nurse provide

ATI RN

ATI Pathophysiology Quizlet

1. A patient is starting on a statin medication for hyperlipidemia. What critical instruction should the nurse provide?

A. Take the medication at night to reduce the risk of muscle pain and other side effects.
B. Take the medication in the morning with breakfast to improve absorption.
C. Avoid alcohol consumption while taking this medication to reduce the risk of liver damage.
D. Take the medication with a high-fat meal to increase its effectiveness.

Correct answer: A

Rationale: The correct answer is A. Statins like atorvastatin should be taken at night to reduce the risk of muscle pain and other side effects. Taking the medication with a high-fat meal (choice D) is not recommended as it can decrease the effectiveness of the medication. Alcohol consumption (choice C) should be moderated but does not need to be completely avoided unless contraindicated. Taking the medication with breakfast (choice B) may not be as effective as taking it at night due to the circadian rhythm of cholesterol synthesis.

2. Which of the following mediates humoral immunity?

A. Natural killer cells
B. T cells
C. B cells
D. Neutrophils

Correct answer: C

Rationale: Humoral immunity is mediated by B cells, not natural killer cells, T cells, or neutrophils. B cells are responsible for producing antibodies, which are essential components of humoral immunity.

3. When educating a client about to undergo a pacemaker insertion, the nurse explains the normal phases of cardiac muscle tissue. During the repolarization phase, the nurse will stress that membranes must be repolarized before they can be re-excited. Within the cell, the nurse understands that:

A. Potassium channels open while sodium channels close, causing repolarization to the resting state.
B. The influx of calcium is the primary stimulus for the repolarization of cardiac tissue.
C. Only the electrical activity within the heart will determine when repolarization occurs.
D. The cell membranes need to stay calm, resulting in muscle tissue becoming refractory.

Correct answer: A

Rationale: During the repolarization phase of cardiac muscle tissue, potassium channels open while sodium channels close. This process is crucial for the cardiac muscle to return to its resting state after depolarization. Potassium moving out of the cell and sodium staying out helps reset the membrane potential and prepare the cell for the next depolarization phase. The influx of calcium is not the primary stimulus for repolarization in cardiac tissue; it is mainly involved in the depolarization phase. While electrical activity within the heart influences repolarization, the specific ion movements described in choice A are what physiologically drive repolarization. Cell membranes need to be in an active state during repolarization, not calm, to facilitate the necessary ion movements for muscle tissue to properly function.

4. An infant is being administered an immunization. Which of the following provides an accurate description of an immunization?

A. It should be administered to a pregnant woman prior to the infant's birth.
B. It is the administration of an antigen to stimulate an antibody response.
C. It produces many adverse reactions, particularly autism, in the infant.
D. It protects the infant from exposure to infectious antibodies.

Correct answer: B

Rationale: The correct answer is B. Immunization involves administering an antigen, such as a weakened or killed microorganism, to stimulate the immune system to produce an antibody response. This process helps the body recognize and remember specific pathogens, providing immunity against future infections. Choice A is incorrect because immunizations are administered to the infant directly, not to the pregnant woman before birth. Choice C is incorrect as there is no scientific evidence linking immunizations to autism. Choice D is incorrect as immunizations protect against infectious agents, not antibodies.

5. Which of the following accurately describes the pathophysiology of asthma?

A. Chronic inflammation of the bronchial lining
B. Narrowing of the airway due to bronchoconstriction
C. Damage to alveoli reducing lung elasticity
D. Overproduction of mucus by the goblet cells

Correct answer: B

Rationale: The correct answer is B: "Narrowing of the airway due to bronchoconstriction." In asthma, there is an inflammatory response that leads to bronchoconstriction, causing the airways to narrow and making it difficult to breathe. Choice A is incorrect as chronic inflammation is a feature of asthma but not the primary pathophysiological mechanism. Choice C is incorrect as damage to alveoli is more characteristic of conditions like emphysema. Choice D is incorrect as overproduction of mucus is a feature of chronic bronchitis, not asthma.