ATI RN
ATI Pathophysiology Exam
1. A patient is prescribed levothyroxine (Synthroid) for hypothyroidism. What is a key point the nurse should include in the patient education?
- A. Take the medication on an empty stomach with a full glass of water to ensure proper absorption.
- B. Do not take this medication with calcium supplements.
- C. Avoid taking this medication with grapefruit juice.
- D. Take the medication with food to enhance absorption.
Correct answer: A
Rationale: The correct answer is A. Levothyroxine should be taken on an empty stomach with a full glass of water, typically 30 minutes to an hour before breakfast, to ensure proper absorption. Taking it with food, calcium supplements, or grapefruit juice can interfere with its absorption. Choice B is incorrect because taking levothyroxine with calcium supplements can reduce its effectiveness. Choice C is incorrect because grapefruit juice can also interfere with levothyroxine absorption. Choice D is incorrect because taking levothyroxine with food can decrease its absorption.
2. What is the distinguishing feature of Hodgkin disease noted on histologic exam?
- A. Reed-Sternberg cells
- B. Red-stained cells
- C. Human Papillomavirus
- D. B-cells and T-cells
Correct answer: A
Rationale: The correct answer is A: Reed-Sternberg cells. Reed-Sternberg cells are large, abnormal B-cells that are characteristic of Hodgkin's lymphoma. These cells are identified on histologic examination of lymph node biopsies from patients with Hodgkin disease. Choice B, 'Red-stained cells,' is vague and does not describe a specific feature of Hodgkin disease. Choice C, 'Human Papillomavirus,' is incorrect as Hodgkin disease is not caused by HPV. Choice D, 'B-cells and T-cells,' is incorrect as Hodgkin disease is characterized by the presence of Reed-Sternberg cells, which are abnormal B-cells.
3. A 22-year-old woman began using oral contraceptives several months ago and has presented for an appointment to discuss recent worrisome changes in her health status. Which of the following changes in the woman's health may the nurse potentially attribute to the use of oral contraceptives?
- A. Fatigue
- B. Frequent high blood pressure readings
- C. Frequent headaches without aura
- D. Nausea and vomiting
Correct answer: A
Rationale: The correct answer is A: Fatigue. Oral contraceptives can sometimes cause fatigue as a side effect. Frequent high blood pressure readings and frequent headaches without aura are less likely to be directly related to the use of oral contraceptives. Nausea and vomiting are common side effects of oral contraceptives but are not the changes typically associated with liver function affecting hormone metabolism as in the case of hepatitis C infection.
4. A 35-year-old female is diagnosed with vitamin B12 deficiency anemia (pernicious anemia). How should the nurse respond when the patient asks what causes pernicious anemia? A decrease in ______ is the most likely cause.
- A. Ferritin
- B. Gastric enzymes
- C. Intrinsic factor
- D. Erythropoietin
Correct answer: C
Rationale: Pernicious anemia is primarily caused by a decrease in intrinsic factor. Intrinsic factor is a protein produced by the stomach that is necessary for the absorption of vitamin B12 in the intestines. Without intrinsic factor, vitamin B12 cannot be absorbed properly, leading to anemia. Ferritin is a protein that stores iron in the body and is not directly related to pernicious anemia. Gastric enzymes play a role in digestion but are not the primary cause of pernicious anemia. Erythropoietin is a hormone produced by the kidneys to stimulate red blood cell production and is not linked to pernicious anemia.
5. What causes osteoporosis?
- A. Poor nutrition in infancy
- B. Regularly weight-bearing exercise
- C. Bone loss, frequently during aging
- D. Cerebral palsy and associated disorders
Correct answer: C
Rationale: The correct answer is C. Osteoporosis is commonly caused by bone loss that occurs with aging, leading to brittle bones. Choice A, poor nutrition in infancy, is not a direct cause of osteoporosis. Choice B, regularly weight-bearing exercise, actually helps in maintaining bone density and strength, reducing the risk of osteoporosis. Choice D, cerebral palsy and associated disorders, is not a common cause of osteoporosis.
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