ATI RN
Proctored Pharmacology ATI
1. A client receiving chemotherapy with Methotrexate asks why Leucovorin is being given. Which of the following responses should the nurse use?
- A. Leucovorin reduces the risk of a transfusion reaction from Methotrexate.
- B. Leucovorin increases platelet production and prevents bleeding.
- C. Leucovorin potentiates the cytotoxic effects of Methotrexate.
- D. Leucovorin protects healthy cells from Methotrexate's toxic effects.
Correct answer: D
Rationale: Leucovorin, a folic acid derivative and an antagonist to Methotrexate, is given within 12 hours of high doses of Methotrexate to protect healthy cells from the toxic effects of Methotrexate. It helps to reduce the bone marrow suppression and gastrointestinal side effects caused by Methotrexate, supporting the client's overall well-being during chemotherapy treatment. Choices A, B, and C are incorrect because Leucovorin does not reduce the risk of a transfusion reaction from Methotrexate, increase platelet production, prevent bleeding, or potentiate the cytotoxic effects of Methotrexate. Instead, Leucovorin works by rescuing healthy cells from the toxic effects of Methotrexate.
2. A client has a new prescription for Captopril. Which of the following instructions should the nurse include?
- A. Take the medication with food.
- B. Monitor your blood pressure weekly.
- C. Notify your provider if you develop a persistent cough.
- D. Avoid using salt substitutes to prevent hyperkalemia.
Correct answer: C
Rationale: The correct answer is to instruct the client to notify the provider if they develop a persistent cough. A persistent cough is a common adverse effect of Captopril and other ACE inhibitors. It is essential for the client to inform their healthcare provider promptly if this side effect occurs, as it may indicate a potentially serious issue that needs medical attention.
3. In an acute mental health facility, a patient experiencing opioid withdrawal has a new prescription for Clonidine. What action should the nurse identify as the priority?
- A. Administer the Clonidine as prescribed.
- B. Provide ice chips to the patient.
- C. Educate the patient on Clonidine's effects.
- D. Obtain baseline vital signs.
Correct answer: D
Rationale: In this scenario, the priority action for the nurse is to obtain baseline vital signs. This is essential for establishing a baseline assessment, especially for a patient undergoing opioid withdrawal and starting a new medication like Clonidine. Monitoring vital signs is crucial for evaluating the patient's response to treatment and detecting any potential complications early on. Administering the medication, providing ice chips, and educating the patient on Clonidine's effects are important tasks but obtaining baseline vital signs takes precedence to ensure the patient's safety and proper management.
4. A client with tobacco use disorder is being educated about Nicotine replacement therapy. Which statement by the client indicates an understanding of the teaching?
- A. I should avoid eating right before chewing a piece of nicotine gum.
- B. I will need to stop using the nicotine gum after 1 year.
- C. I know that nicotine gum is a safe alternative to smoking during pregnancy.
- D. I must chew the nicotine gum quickly for about 15 minutes.
Correct answer: A
Rationale: The correct answer is A. To maximize the effectiveness of nicotine gum, the client should avoid eating or drinking 15 minutes before and while using it. This helps ensure proper absorption of nicotine through the oral mucosa. Choice B is incorrect because the duration of nicotine gum use can vary depending on the individual's needs and progress. Choice C is incorrect as nicotine gum should be used during pregnancy only under healthcare provider guidance. Choice D is incorrect because nicotine gum should be chewed slowly until a tingling sensation is felt, then parked between the cheek and gum until the tingling stops.
5. A client in a critical care unit is postoperative following a right pneumonectomy. After extubation from the ventilator, in which of the following positions should the client be placed?
- A. Prone
- B. On the nonoperative side
- C. Sims'
- D. Semi-Fowler's
Correct answer: D
Rationale: After a pneumonectomy, positioning the client in a semi-Fowler's position is crucial for optimal ventilation. This position helps improve lung expansion on the remaining side, facilitating better oxygenation and preventing complications like atelectasis. Placing the client prone, on the nonoperative side, or in Sims' position would not provide the same respiratory benefits post-pneumonectomy.
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