ATI RN
Proctored Pharmacology ATI
1. A client receiving chemotherapy with Methotrexate asks why Leucovorin is being given. Which of the following responses should the nurse use?
- A. Leucovorin reduces the risk of a transfusion reaction from Methotrexate.
- B. Leucovorin increases platelet production and prevents bleeding.
- C. Leucovorin potentiates the cytotoxic effects of Methotrexate.
- D. Leucovorin protects healthy cells from Methotrexate's toxic effects.
Correct answer: D
Rationale: Leucovorin, a folic acid derivative and an antagonist to Methotrexate, is given within 12 hours of high doses of Methotrexate to protect healthy cells from the toxic effects of Methotrexate. It helps to reduce the bone marrow suppression and gastrointestinal side effects caused by Methotrexate, supporting the client's overall well-being during chemotherapy treatment. Choices A, B, and C are incorrect because Leucovorin does not reduce the risk of a transfusion reaction from Methotrexate, increase platelet production, prevent bleeding, or potentiate the cytotoxic effects of Methotrexate. Instead, Leucovorin works by rescuing healthy cells from the toxic effects of Methotrexate.
2. A client has a prescription for Clonidine to treat hypertension. Which of the following instructions should the nurse include?
- A. Discontinue the medication if you experience dry mouth.
- B. Take the medication at the same time each day.
- C. Double the dose if you miss a dose.
- D. Avoid drinking orange juice while taking this medication.
Correct answer: B
Rationale: Correct Answer: Taking Clonidine at the same time each day is crucial to ensure consistent blood levels and effectively manage blood pressure. Consistency in timing helps optimize the medication's effectiveness in controlling hypertension.
3. A client is starting a new prescription for furosemide. Which of the following instructions should the nurse include?
- A. Weigh yourself daily.
- B. Limit sodium intake.
- C. Increase potassium intake.
- D. Avoid potassium-rich foods.
Correct answer: A
Rationale: The correct instruction to include when starting furosemide is to weigh yourself daily. Daily weighing helps monitor for fluid loss or retention, which is crucial when taking a diuretic like furosemide. Choices B, C, and D are incorrect because although monitoring sodium intake and potassium levels are important when taking furosemide, the most immediate and direct way to assess the medication's effectiveness and the body's response is through daily weight monitoring.
4. When teaching parents of a school-age child about transdermal Methylphenidate, which instruction should the nurse include?
- A. Apply one patch once per day.
- B. Leave the patch on for 9 hours.
- C. Apply the patch to the child's waistline.
- D. Use the opened tray within 6 months.
Correct answer: B
Rationale: When administering transdermal Methylphenidate, the patch should be left on for 9 hours per day to ensure optimal absorption and effectiveness of the medication. This duration helps maintain a consistent level of the drug in the child's system. Incorrect options: A) Applying one patch once per day is not the correct dosing regimen for transdermal Methylphenidate. C) The patch should not be applied to the child's waistline as it is recommended to apply it to a clean, dry area. D) Using the opened tray within 6 months is not directly related to the administration of transdermal Methylphenidate.
5. A healthcare professional is preparing to administer vancomycin to a client. The professional should monitor for which of the following adverse effects?
- A. Nephrotoxicity
- B. Hepatotoxicity
- C. Red Man Syndrome
- D. Diarrhea
Correct answer: C
Rationale: Red Man Syndrome is a common adverse effect of vancomycin characterized by flushing and rash. It is not related to nephrotoxicity, hepatotoxicity, or diarrhea. Monitoring for this reaction allows for prompt intervention to prevent severe complications.
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