ATI RN
Proctored Pharmacology ATI
1. A client receiving chemotherapy with Methotrexate asks why Leucovorin is being given. Which of the following responses should the nurse use?
- A. Leucovorin reduces the risk of a transfusion reaction from Methotrexate.
- B. Leucovorin increases platelet production and prevents bleeding.
- C. Leucovorin potentiates the cytotoxic effects of Methotrexate.
- D. Leucovorin protects healthy cells from Methotrexate's toxic effects.
Correct answer: D
Rationale: Leucovorin, a folic acid derivative and an antagonist to Methotrexate, is given within 12 hours of high doses of Methotrexate to protect healthy cells from the toxic effects of Methotrexate. It helps to reduce the bone marrow suppression and gastrointestinal side effects caused by Methotrexate, supporting the client's overall well-being during chemotherapy treatment. Choices A, B, and C are incorrect because Leucovorin does not reduce the risk of a transfusion reaction from Methotrexate, increase platelet production, prevent bleeding, or potentiate the cytotoxic effects of Methotrexate. Instead, Leucovorin works by rescuing healthy cells from the toxic effects of Methotrexate.
2. What is the correct medical term used to describe impaired blood flow in the coronary arteries?
- A. Myocardial infarction
- B. Angina pectoris
- C. Cerebrovascular accident
- D. Coronary heart disease
Correct answer: D
Rationale: The correct medical term for impaired blood flow in the coronary arteries is Coronary heart disease. This condition is characterized by a narrowing or blockage of the coronary arteries, leading to reduced blood flow to the heart muscle. Myocardial infarction (choice A) refers to a heart attack, which occurs when blood flow to a part of the heart is blocked. Angina pectoris (choice B) is chest pain or discomfort that occurs when the heart muscle doesn't receive enough oxygen-rich blood. Cerebrovascular accident (choice C) is the medical term for a stroke, which occurs when blood flow to a part of the brain is interrupted.
3. A healthcare professional is providing discharge instructions to a client who has a new prescription for Furosemide. Which of the following instructions should the healthcare professional include?
- A. Take the medication with breakfast.
- B. Increase intake of foods high in potassium.
- C. Avoid prolonged sun exposure.
- D. Limit sodium intake.
Correct answer: B
Rationale: The correct answer is B: 'Increase intake of foods high in potassium.' Furosemide, a loop diuretic, can cause potassium depletion. The healthcare professional should instruct the client to increase the intake of foods high in potassium to prevent hypokalemia, a potential side effect of Furosemide therapy. Choice A is incorrect as Furosemide is usually recommended to be taken in the morning to prevent nocturia. Choice C is unrelated to the side effects of Furosemide. Choice D, while important for overall health, is not directly related to the side effects of Furosemide.
4. A client has a new prescription for nitroglycerin sublingual tablets. Which of the following instructions should the nurse include?
- A. Take one tablet at the first sign of chest pain.
- B. If pain is not relieved, take another tablet in 10 minutes.
- C. You can take up to five tablets in 15 minutes.
- D. Swallow the tablet with water.
Correct answer: A
Rationale: The correct instruction for a client with a new prescription for nitroglycerin sublingual tablets is to take one tablet at the first sign of chest pain. If the pain persists after 5 minutes, the client should call 911 and take a second tablet. Choice A is correct because taking one tablet at the onset of chest pain helps to relieve symptoms by dilating blood vessels and improving blood flow to the heart. Choices B and C are incorrect as they suggest taking multiple tablets without waiting for the initial dose to take effect, which can lead to hypotension and other adverse effects. Choice D is incorrect as nitroglycerin sublingual tablets should not be swallowed but instead placed under the tongue for rapid absorption.
5. A client is receiving Morphine IV for pain management. Which of the following actions should the nurse take?
- A. Monitor the client's respiratory rate every 15 minutes.
- B. Monitor the client's blood pressure every 30 minutes.
- C. Monitor the client's oxygen saturation every hour.
- D. Monitor the client's heart rate every 5 minutes.
Correct answer: A
Rationale: The correct action for the nurse is to monitor the client's respiratory rate every 15 minutes while on Morphine IV to promptly detect respiratory depression, a critical adverse effect associated with this medication. Respiratory depression is a common side effect of opioid medications like Morphine and can be life-threatening. Monitoring the respiratory rate frequently enables the nurse to identify early signs of respiratory compromise and intervene promptly. Monitoring other vital signs like blood pressure, oxygen saturation, or heart rate is important but not as crucial as monitoring respiratory rate when a client is on Morphine IV.
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