ATI RN
ATI Pharmacology
1. A healthcare professional is preparing to administer clindamycin 200 mg by intermittent IV bolus. The amount available is clindamycin injection 200 mg in 100 mL 0.9% sodium chloride (0.9% NaCl) to infuse over 30 min. How many mL/hr should the IV pump be set to deliver?
- A. 200 mL/hr
- B. 150 mL/hr
- C. 100 mL/hr
- D. 250 mL/hr
Correct answer: A
Rationale: To calculate the flow rate in mL/hr: (Volume in mL / Time in hours) = Flow rate in mL/hr. In this case, (100 mL / 0.5 hr) = 200 mL/hr. Therefore, the IV pump should be set to deliver 200 mL/hr to administer clindamycin 200 mg over 30 minutes. Choice A is correct because it provides the accurate flow rate needed for the administration of the medication. Choices B, C, and D are incorrect as they do not calculate the flow rate correctly based on the volume and time specified in the question.
2. When assessing a client with chronic Neutropenia receiving Filgrastim, what action should the nurse take to evaluate for an adverse effect of the medication?
- A. Assess for bone pain.
- B. Assess for right lower quadrant pain.
- C. Auscultate for crackles in the bases of the lungs.
- D. Auscultate the chest to listen for a heart murmur.
Correct answer: A
Rationale: The correct action when assessing a client receiving Filgrastim for chronic Neutropenia is to assess for bone pain. Bone pain is a known dose-related adverse effect of Filgrastim. Acetaminophen or opioid analgesics can be used to manage bone pain if necessary. Assessing for other types of pain, lung crackles, or heart murmurs would not be specific to the adverse effects of Filgrastim.
3. In which patient could the drug Senna potentially be indicated?
- A. A patient with an eating disorder
- B. A patient who has not passed stool in 5 days
- C. A patient with anal fissures
- D. A patient with a history of hemorrhoids
Correct answer: B
Rationale: Senna is a stimulant laxative commonly used to treat constipation by stimulating bowel movements. It is typically indicated for patients who have not passed stool in several days, thereby helping to relieve constipation. Patients with eating disorders may require different treatments related to their condition. Patients with anal fissures or a history of hemorrhoids may need treatments targeted at those specific issues, which may not involve Senna.
4. A client has a new prescription for Nitrofurantoin. Which of the following instructions should the nurse include?
- A. Take this medication with food.
- B. Avoid dairy products while taking this medication.
- C. Take this medication at bedtime.
- D. Increase your intake of vitamins.
Correct answer: A
Rationale: The correct instruction for a client prescribed Nitrofurantoin is to take the medication with food. Taking Nitrofurantoin with food helps enhance absorption and reduces the risk of gastrointestinal side effects. It is important for the nurse to emphasize this instruction to ensure the client benefits optimally from the medication. Choices B, C, and D are incorrect. Avoiding dairy products is not specifically required with Nitrofurantoin. Taking the medication at bedtime is not a standard instruction. Increasing vitamin intake is not necessary in relation to Nitrofurantoin therapy.
5. What is the pharmacological action of metformin?
- A. Blocks stimulation of beta1 and beta2.
- B. Blocks vasoconstriction and aldosterone.
- C. Acts at many levels in the CNS to produce an anxiolytic effect.
- D. Decreases hepatic glucose production.
Correct answer: D
Rationale: The correct answer is D: Decreases hepatic glucose production. Metformin's primary pharmacological action is to decrease hepatic glucose production, leading to lower blood sugar levels and improved insulin sensitivity in the liver. Choices A, B, and C are incorrect because metformin does not block stimulation of beta1 and beta2 receptors, vasoconstriction, aldosterone, or act in the CNS to produce an anxiolytic effect. Therefore, these options are not reflective of metformin's mechanism of action.
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