ATI RN
ATI Pharmacology
1. A nurse is evaluating teaching for a client who has Rheumatoid Arthritis and a new prescription for Methotrexate. Which of the following statements by the client indicates understanding of the teaching?
- A. I will be sure to return to the clinic at least once a year to have my blood drawn while I'm taking methotrexate.
- B. I will take this medication on an empty stomach.
- C. I'll let the doctor know if I develop sores in my mouth while taking this medication.
- D. I should stop taking oral contraceptives while I'm taking methotrexate.
Correct answer: C
Rationale: Ulcerations in the mouth, tongue, or throat are often the first signs of methotrexate toxicity and should be reported to the provider immediately.
2. A client has a new prescription for Methotrexate. Which of the following instructions should be included in the teaching?
- A. Avoid drinking alcohol while taking this medication.
- B. Take the medication with a high-fat meal.
- C. Expect increased hair growth.
- D. You should never stop taking the medication without consulting your healthcare provider.
Correct answer: A
Rationale: The correct instruction for a client taking Methotrexate is to avoid drinking alcohol. Methotrexate can cause liver toxicity, and alcohol consumption can increase this risk. It is important to emphasize the avoidance of alcohol while on this medication to prevent adverse effects and ensure treatment effectiveness. The other options are incorrect: Taking Methotrexate with a high-fat meal is not necessary as it can be taken with or without food. Increased hair growth is not an expected effect of Methotrexate; in fact, hair loss is a potential side effect. Stopping the medication without consulting a healthcare provider can be dangerous and may lead to worsening of symptoms or relapse, making option D incorrect.
3. Which adverse reaction poses the greatest life-threatening risk when taking Omeprazole?
- A. Chest pain
- B. Constipation
- C. Clostridium difficile-associated diarrhea
- D. Acute interstitial nephritis
Correct answer: C
Rationale: The most life-threatening adverse reaction associated with Omeprazole is Clostridium difficile-associated diarrhea. This condition can be severe and life-threatening due to the potential for dehydration, electrolyte imbalances, and complications such as toxic megacolon. Chest pain, constipation, and acute interstitial nephritis are potential side effects of Omeprazole but are not considered as life-threatening as Clostridium difficile-associated diarrhea. Monitoring for signs of this adverse reaction is crucial, and immediate medical attention should be sought if symptoms develop.
4. A client with peptic ulcer disease is prescribed sucralfate. Which of the following instructions should the nurse include?
- A. Take sucralfate with meals.
- B. Take sucralfate 1 hr before meals.
- C. Take sucralfate with antacids.
- D. Take sucralfate 2 hours after meals.
Correct answer: B
Rationale: The correct instruction for taking sucralfate is 1 hour before meals. This timing allows sucralfate to effectively coat the stomach lining and provide a protective barrier against gastric acid, helping to prevent ulcers.
5. A male client recently started taking Haloperidol. Which of the following findings is the highest priority to report to the provider?
- A. Shuffling gait
- B. Neck spasms
- C. Drowsiness
- D. Impotence
Correct answer: B
Rationale: Neck spasms are an indication of acute dystonia, a serious side effect of Haloperidol that can quickly progress to a crisis situation. Immediate medical attention is necessary to prevent complications. Shuffling gait and drowsiness are common side effects of Haloperidol but are not as urgent as neck spasms. Impotence is not typically associated with Haloperidol use. Therefore, identifying neck spasms as the priority finding is crucial for the client's safety.
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