a nurse is caring for a client who has a new prescription for enalapril which of the following adverse effects should the nurse monitor

ATI RN

ATI Pharmacology

1. A client has a new prescription for Enalapril. Which of the following adverse effects should the nurse monitor?

A. Dry cough
B. Weight gain
C. Diarrhea
D. Nausea

Correct answer: A

Rationale: The correct answer is A: Dry cough. A persistent dry cough is a common adverse effect of Enalapril, an ACE inhibitor. Enalapril can cause the accumulation of bradykinin, leading to cough. Monitoring for a persistent dry cough is crucial as it may indicate the need for further evaluation and possible medication adjustment. Choices B, C, and D are not typically associated with Enalapril use and are less likely to be monitored as adverse effects.

2. A client is prescribed Metformin. Which of the following laboratory values should be monitored to assess for potential adverse effects?

A. Blood glucose
B. Creatine kinase
C. Hemoglobin A1c
D. Serum creatinine

Correct answer: D

Rationale: The correct answer is D: Serum creatinine. Metformin can potentially cause lactic acidosis, particularly in patients with impaired renal function. Monitoring serum creatinine levels is crucial to assess kidney function and detect any adverse effects of Metformin on renal health. Choices A, B, and C are incorrect as blood glucose, creatine kinase, and hemoglobin A1c levels are not directly monitored to assess for potential adverse effects of Metformin. Blood glucose monitoring is typically done to assess the efficacy of antidiabetic medications like Metformin, while creatine kinase levels are indicative of muscle damage and hemoglobin A1c reflects long-term blood sugar control.

3. A healthcare professional is obtaining a medication history from a client who is to receive Imipenem-cilastatin IV to treat an infection. Which of the following medications the client also receives puts them at risk for a medication interaction?

A. Regular insulin
B. Furosemide
C. Valproic acid
D. Ferrous sulfate

Correct answer: C

Rationale: The correct answer is C, Valproic acid. Imipenem-cilastatin decreases the blood levels of valproic acid, an antiseizure medication, which can lead to increased seizure activity. Monitoring and adjusting the dosage of valproic acid may be necessary when co-administered with Imipenem-cilastatin to prevent adverse effects. Choices A, B, and D do not typically interact significantly with Imipenem-cilastatin and are not associated with a high risk of adverse interactions in this scenario.

4. Which of the following is the antidote for benzodiazepine toxicity?

A. Flumazenil
B. Methylene blue
C. Deferoxamine
D. Alkalinize urine

Correct answer: A

Rationale: Flumazenil is the specific antidote for benzodiazepine toxicity. It acts as a competitive antagonist at the benzodiazepine binding site on the GABA receptor, reversing the sedative effects of benzodiazepines. Administration of flumazenil is indicated in cases of benzodiazepine overdose or toxicity to rapidly reverse the central nervous system depression caused by these drugs. It is important to note that flumazenil should be used cautiously in patients with a history of seizures or those who are physically dependent on benzodiazepines, as it can precipitate withdrawal symptoms or seizures.

5. Which of the following conditions is not treated with Ephedrine?

A. COPD
B. Hypotension
C. Congestion
D. Incontinence

Correct answer: A

Rationale: Ephedrine is not typically used to treat COPD. While it can help relieve symptoms like congestion and hypotension, it is not a first-line treatment for COPD. Incontinence is not a condition commonly treated with Ephedrine either.