ATI RN
ATI Pathophysiology
1. A male patient with erectile dysfunction has asked for a prescription for sildenafil (Viagra). Before giving this medication, the nurse should assess for which of the following conditions?
- A. History of peptic ulcer disease
- B. Use of nitrates
- C. Recent history of a stroke
- D. History of hypertension
Correct answer: B
Rationale: The correct answer is B: Use of nitrates. Sildenafil should not be used by patients taking nitrates due to the risk of severe hypotension. Nitrates can potentiate the hypotensive effects of sildenafil, leading to a significant drop in blood pressure. Assessing for the use of nitrates is crucial to avoid this potentially dangerous interaction. Choices A, C, and D are incorrect because they are not specifically contraindications for the use of sildenafil. While a history of hypertension should be considered, it is not as critical as the use of nitrates when prescribing sildenafil.
2. When planning care for a cardiac patient, the nurse knows that in response to an increased workload, cardiac myocardial cells will:
- A. Increase in size
- B. Decrease in length
- C. Increase in excitability
- D. Increase in number
Correct answer: A
Rationale: The correct answer is A: Increase in size. Cardiac hypertrophy occurs when myocardial cells increase in size to compensate for an increased workload. This adaptation allows the heart to pump more effectively. Choice B, Decrease in length, is incorrect as cardiac cells do not decrease in length in response to increased workload. Choice C, Increase in excitability, is incorrect as increased workload does not lead to an increase in excitability of cardiac cells. Choice D, Increase in number, is incorrect as cardiac cells do not increase in number but rather increase in size to handle the increased workload.
3. A nurse practitioner is seeing a client in the clinic with a suspected diagnosis of bacterial meningitis. What should the nurse anticipate as the priority action?
- A. Administer the first dose of antibiotics immediately after blood cultures are drawn.
- B. Start an IV line and administer corticosteroids to reduce inflammation.
- C. Isolate the client to prevent the spread of infection.
- D. Perform a lumbar puncture to confirm the diagnosis.
Correct answer: A
Rationale: The correct answer is to administer the first dose of antibiotics immediately after blood cultures are drawn for suspected bacterial meningitis. This is crucial to initiate treatment promptly and improve patient outcomes. Starting an IV line and administering corticosteroids (Choice B) may be part of the treatment plan but administering antibiotics is the priority. Isolating the client (Choice C) is important to prevent the spread of infection but not the priority over initiating antibiotic therapy. Performing a lumbar puncture (Choice D) may confirm the diagnosis, but treatment should not be delayed for this step in suspected cases of bacterial meningitis.
4. In a postmenopausal woman, what condition can be prevented by administering estradiol (Estraderm)?
- A. Endometriosis
- B. Amenorrhea
- C. Osteoporosis
- D. Uterine cancer
Correct answer: C
Rationale: The correct answer is C: Osteoporosis. Estradiol, a form of estrogen, is used to prevent osteoporosis in postmenopausal women by maintaining bone density. Choice A, Endometriosis, is incorrect as estradiol is not used to prevent or treat this condition. Choice B, Amenorrhea, is not prevented by estradiol but rather may result from hormonal changes. Choice D, Uterine cancer, is not directly prevented by estradiol; in fact, long-term unopposed estrogen use can increase the risk of uterine cancer.
5. What is the main function of the mitochondria in a cell?
- A. To produce energy in the form of ATP
- B. To synthesize proteins
- C. To store genetic information
- D. To regulate cell growth
Correct answer: A
Rationale: The correct answer is A: To produce energy in the form of ATP. Mitochondria are known as the powerhouse of the cell because they are responsible for producing energy in the form of ATP through a process called cellular respiration. This energy is essential for various cellular activities. Choice B is incorrect because protein synthesis primarily occurs in the ribosomes. Choice C is incorrect as the genetic information is stored in the cell's nucleus. Choice D is incorrect as the regulation of cell growth involves various other organelles and processes within the cell.
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