ATI RN
Pathophysiology Practice Questions
1. What is a cause of the crystallization within the synovial fluid of the joint affected by gouty arthritis?
- A. Destruction of proteoglycans
- B. Underexcretion of uric acid
- C. Overexcretion of uric acid
- D. Increased absorption of uric acid
Correct answer: B
Rationale: The correct answer is B: Underexcretion of uric acid. Gouty arthritis is primarily caused by the underexcretion of uric acid, leading to its accumulation in joints and subsequent crystallization. Choices A, C, and D are incorrect as they do not directly relate to the pathophysiology of gout. Destruction of proteoglycans, overexcretion of uric acid, and increased absorption of uric acid are not primary causes of gouty arthritis.
2. A client in a clinic presents with an acute asthma exacerbation. Which of the following medications should reduce the symptoms?
- A. Cromolyn via a metered-dose inhaler
- B. Montelukast orally
- C. Budesonide via a dry-powder inhaler
- D. Albuterol via a jet nebulizer
Correct answer: Albuterol via a jet nebulizer
Rationale: During an acute asthma exacerbation, the preferred medication for symptom relief is a short-acting beta-agonist like albuterol, typically delivered via a jet nebulizer for quick onset and efficacy. Cromolyn, montelukast, and budesonide are not as effective for immediate symptom relief in acute exacerbations and are more commonly used for prevention or long-term management of asthma symptoms.
3. What is a chronic condition where the blood pressure in the arteries is persistently elevated, increasing the risk of heart disease and stroke?
- A. Hypertension
- B. Hypotension
- C. Hyperlipidemia
- D. Hyperglycemia
Correct answer: A
Rationale: Hypertension, also known as high blood pressure, is a chronic condition characterized by persistently elevated pressure in the arteries. This condition increases the risk of heart disease, stroke, and other health issues. Hypotension (choice B) refers to low blood pressure and is not the correct answer. Hyperlipidemia (choice C) is high levels of fats in the blood, not related to blood pressure. Hyperglycemia (choice D) is high blood sugar levels, not directly related to elevated blood pressure.
4. Which of the following would the nurse see in a client with thrombocytopenia?
- A. A decreased platelet cell count
- B. Decreased white blood cell count
- C. Increased red blood cell count
- D. An increased platelet cell count
Correct answer: A
Rationale: Thrombocytopenia is characterized by a decreased platelet cell count, leading to an increased risk of bleeding. Therefore, the correct answer is A. Choice B, a decreased white blood cell count, is not typically associated with thrombocytopenia. Choice C, an increased red blood cell count, is not a characteristic finding in thrombocytopenia. Choice D, an increased platelet cell count, is the opposite of what is observed in thrombocytopenia.
5. A client is admitted to the hospital with a suspected diagnosis of Hodgkin’s disease. Which assessment finding would the nurse expect to note specifically in the client?
- A. Fatigue
- B. Weakness
- C. Weight gain
- D. Enlarged lymph nodes
Correct answer: D
Rationale: Hodgkin’s disease (Hodgkin’s lymphoma) is a type of cancer that originates in the lymphatic system, particularly affecting the lymph nodes. A hallmark sign of Hodgkin’s disease is the painless enlargement of lymph nodes, often in the neck, armpit, or groin. These enlarged lymph nodes are typically firm and rubbery to the touch. This is one of the most distinctive and common early signs that healthcare providers look for when diagnosing the disease.
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