ATI RN
Final Exam Pathophysiology
1. A 69-year-old female patient has been diagnosed with malignant melanoma. The care team has collaborated with the patient and her family and agreed on a plan of care that includes administration of interferon alfa-2b. After administering interferon alfa-2b, the oncology nurse should anticipate that the patient may develop which of the following adverse effects?
- A. Profound diaphoresis
- B. Decreased level of consciousness
- C. Flu-like symptoms
- D. Cyanosis and pallor
Correct answer: C
Rationale: After the administration of interferon alfa-2b, the patient may develop flu-like symptoms as an adverse effect. Flu-like symptoms are commonly associated with interferon therapy, including fever, chills, fatigue, and muscle aches. These symptoms usually subside over time. Options A, B, and D are not typically associated with interferon alfa-2b administration. Profound diaphoresis is excessive sweating, decreased level of consciousness indicates neurological issues, and cyanosis and pallor suggest circulatory or respiratory problems, none of which are expected adverse effects of interferon alfa-2b.
2. A client with a new diagnosis of peptic ulcer disease is receiving teaching from a nurse. Which of the following statements by the client indicates an understanding of the teaching?
- A. I will avoid taking ibuprofen for my pain.
- B. I will avoid eating spicy foods.
- C. I will limit my intake of dairy products.
- D. I will take my antacids 30 minutes before meals.
Correct answer: B
Rationale: The correct answer is B. Clients with peptic ulcer disease should avoid spicy foods as they can exacerbate symptoms and delay healing. Ibuprofen can worsen peptic ulcers by irritating the stomach lining, so it should be avoided. While limiting dairy products may be beneficial for some individuals with lactose intolerance, it is not a specific recommendation for peptic ulcer disease. Taking antacids before meals can help neutralize stomach acid; however, the timing may vary depending on the type of antacid, so there is no universal rule of taking antacids 30 minutes before meals. Choice A is incorrect because the client should avoid taking ibuprofen due to its potential to worsen peptic ulcers. Choice C is incorrect as there is no direct correlation between dairy product intake and peptic ulcer disease. Choice D is incorrect because the timing of antacid administration can vary and should be guided by specific recommendations.
3. A community health nurse is providing an educational session on childhood poisoning at a local school. What should the nurse advise as the first action if poisoning occurs?
- A. Call the poison control center
- B. Bring the child to the emergency department (ED)
- C. Induce vomiting
- D. Call an ambulance
Correct answer: A
Rationale: In the event of poisoning, the recommended first action is to call the poison control center. Poison control specialists can provide immediate guidance on how to manage the situation effectively. Bringing the child to the emergency department (Choice B) may be necessary depending on the severity of the poisoning, but contacting poison control first is crucial for appropriate and timely intervention. Inducing vomiting (Choice C) is not advised in all cases of poisoning and should only be done under the guidance of healthcare professionals. Calling an ambulance (Choice D) may be necessary in some severe cases, but the initial step should be to contact poison control for expert advice.
4. Sickle cell disease is an example of an inherited mistake in the amino acid sequence.
- A. TRUE
- B. FALSE
- C.
- D.
Correct answer: A
Rationale: The statement is TRUE. Sickle cell disease is caused by a genetic mutation in the hemoglobin gene, leading to an abnormal amino acid sequence. This results in the production of abnormal hemoglobin molecules, causing red blood cells to become sickle-shaped. This inherited condition is a classic example of a genetic error affecting the amino acid sequence, making choice A the correct answer. Choices B, C, and D are incorrect as they do not accurately reflect the nature of sickle cell disease.
5. A healthcare professional is reviewing the medical record of a client with a new prescription for Epoetin Alfa. Which of the following findings should the professional report to the provider?
- A. The client has a history of hypertension.
- B. The client has a hemoglobin level of 10 g/dL.
- C. The client has a history of chronic kidney disease.
- D. The client has a blood pressure of 140/90 mm Hg.
Correct answer: C
Rationale: The correct answer is C. Chronic kidney disease is a contraindication for the use of Epoetin Alfa because it can worsen hypertension, increase the risk of cardiovascular events, and lead to adverse outcomes. Epoetin Alfa is used to treat anemia by stimulating red blood cell production, but in the presence of chronic kidney disease, it can exacerbate hypertension and contribute to cardiovascular complications. Choices A, B, and D are not directly related to the contraindication of Epoetin Alfa in the presence of chronic kidney disease.
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