in which patient is alpha 1 antitrypsin deficiency the likely cause of chronic obstructive pulmonary disease in which patient is alpha 1 antitrypsin deficiency the likely cause of chronic obstructive pulmonary disease
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MSN 570 Advanced Pathophysiology Final 2024

1. In which patient is alpha-1 antitrypsin deficiency the likely cause of chronic obstructive pulmonary disease?

Correct answer: A 30-year-old who has smoked for 3 years

Rationale: Alpha-1 antitrypsin deficiency is a genetic cause of chronic obstructive pulmonary disease (COPD). It is more common in younger patients with a history of smoking at a younger age, like the 30-year-old who has smoked for 3 years. Choices B, C, and D are less likely to be associated with alpha-1 antitrypsin deficiency as COPD in these cases is more likely due to smoking and environmental exposures.

2. A 25-year-old woman who works as an air traffic controller presents with facial pain and severe headache. She reports that she sometimes feels the pain in her neck or ear and that it is particularly bad during very busy times at the airport. What is the most likely diagnosis?

Correct answer: C

Rationale: The most likely diagnosis for the 25-year-old woman who works as an air traffic controller and presents with facial pain and severe headache that sometimes radiates to her neck or ear, aggravated by stress, is Temporomandibular joint syndrome. This syndrome involves pain in the jaw joint and the muscles controlling jaw movement, which can radiate to the surrounding areas like the neck and ear. Stress and clenching of the jaw commonly exacerbate the symptoms. Migraine headache (choice A) typically presents with other symptoms like nausea, sensitivity to light or sound, and can be triggered by various factors, not just stress. Cluster headache (choice B) is characterized by severe, unilateral pain around the eye with associated autonomic symptoms. Sinus headache (choice D) is usually associated with sinus congestion or infection, presenting with facial pressure or pain, often worsened by bending forward.

3. To study the impact of biological aging on motor skills, researchers focus on __________.

Correct answer: B

Rationale: The correct answer is B: competitive athletes. Competitive athletes are often studied by researchers to investigate the impact of biological aging on motor skills because their performance is closely linked to physical abilities. Sedentary adults (choice A) may not provide a clear understanding of the relationship between biological aging and motor skills as they may not engage in consistent physical activity. Men in their mid- to late thirties (choice C) and women in their childbearing years (choice D) may not represent a group where motor skills are as finely tuned and critical to performance as in competitive athletes.

4. Which systemic disease is best controlled with the DASH diet, monitoring blood pressure, limiting sodium, alcohol, and caffeine, reducing stress, and losing weight?

Correct answer: A

Rationale: The correct answer is A: Hypertension. The DASH diet is specifically designed to control hypertension by reducing sodium intake, managing blood pressure, and promoting overall cardiovascular health. Choice B, Diabetes mellitus, is managed through monitoring blood sugar levels and a balanced diet rich in whole grains, fruits, and vegetables. Choice C, Parkinson's disease, is a neurological disorder that is not primarily managed through diet modifications. Choice D, Anemia, is a condition characterized by a lack of healthy red blood cells and is typically managed by addressing the underlying cause and sometimes iron supplementation, not by the methods mentioned in the question.

5. What is the medical term for a persistent, abnormal distortion of taste?

Correct answer: B: Dysgeusia

Rationale: The correct answer is Dysgeusia, which is a persistent and abnormal distortion of the sense of taste. This condition can be triggered by various factors such as medications or certain diseases. Anosmia, choice A, refers to the loss of the sense of smell, not taste. Xerostomia, choice C, is the medical term for dry mouth, which is not specifically related to a distortion of taste. Hypogeusia, choice D, refers to a reduced ability to taste things, which is not the same as a distortion of the sense of taste.

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